The NIDDK is offering this grant for innovative basic and translational pilot research on HIV/AIDS, specifically within its mission and aligned with NIH HIV/AIDS research priorities. This grant supports studies investigating unique pathophysiological mechanisms of HIV comorbidities, coinfections, and complications (CCCs) affecting NIDDK-relevant organs and tissues. It also focuses on exploring biological mechanisms of HIV reservoirs in NIDDK-relevant tissues, crucial for developing long-term viral suppression or eradication strategies. Furthermore, research on how social determinants of health influence CCCs or viral reservoirs within NIDDK’s mission is encouraged.
Opportunity ID: 358082
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-068 |
| Funding Opportunity Title: | Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 08, 2025 |
| Last Updated Date: | Jan 08, 2025 |
| Original Closing Date for Applications: | Jan 07, 2028 |
| Current Closing Date for Applications: | Jan 07, 2028 |
| Archive Date: | Feb 12, 2028 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses Small businesses Special district governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) invites applications for innovative basic and translational pilot research projects within the mission of the NIDDK that are aligned with NIH HIV/AIDS research priorities. These priorities were most recently outlined by the NIH Office of AIDS Research (OAR) in NOT-20-018, UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding, scientific priorities. Potential topics could address multiple overarching priorities. These include elucidation of unique pathophysiological mechanisms contributing to HIV comorbidities, coinfections, and complications (CCCs) affecting organs, tissues, and processes within the mission of the NIDDK. Likewise, interrogations into biological mechanisms underlying HIV reservoirs in NIDDK-relevant tissues are important for developing strategies for long-term viral suppression or eradication. Finally, health-impeding social determinants of health may affect CCCs or viral reservoirs within NIDDK’s mission through multiple pathways. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-068.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358082 Full Announcement-PAR-25-068 -> PAR-25-068-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289951 | Apr 07, 2025 | Jan 07, 2028 | View |
Package 1
Mandatory forms
358082 RR_SF424_5_0-5.0.pdf
358082 PHS398_CoverPageSupplement_5_0-5.0.pdf
358082 RR_OtherProjectInfo_1_4-1.4.pdf
358082 PerformanceSite_4_0-4.0.pdf
358082 RR_KeyPersonExpanded_4_0-4.0.pdf
358082 PHS398_ResearchPlan_5_0-5.0.pdf
358082 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358082 RR_Budget_3_0-3.0.pdf
358082 RR_SubawardBudget30_3_0-3.0.pdf
358082 PHS398_ModularBudget_1_2-1.2.pdf
358082 PHS_AssignmentRequestForm_4_0-4.0.pdf
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