The NIDDK is offering this grant to renew the Inflammatory Bowel Disease Genetics Consortium (IBDGC) and its Genetic Research Centers (GRCs). Established in 2002, the IBDGC has identified over 100 IBD susceptibility loci. This grant is for continuing the discovery of new genetic variants linked to IBD and, crucially, to understand how these variants influence the disease’s pathophysiology. This will be achieved by integrating genomic data with epigenomic, transcriptomic, proteomic, and metabolomic methodologies. The GRCs will enroll IBD patients, relatives, and controls, conducting laboratory studies on their biological samples. PD(s)/PI(s) will serve on the IBDGC Steering Committee, guiding operational decisions.
Opportunity ID: 143254
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-11-032 |
| Funding Opportunity Title: | NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genetic Research Centers (GRCs) (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 09, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 30, 2012 |
| Current Closing Date for Applications: | Apr 30, 2012 |
| Archive Date: | May 31, 2012 |
| Estimated Total Program Funding: | $2,250,000 |
| Award Ceiling: | $250,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) was established in July, 2002 for the purpose of identifying genes predisposing to IBD.Since its establishment, the IBDGC, in collaboration with other international IBD genetics consortia, has identified more than 100 such susceptibility loci.However, many susceptibility genes still remain to be identified, and the work of elucidating how IBD risk-associated genetic variants influence the pathophysiology of IBD has barely begun.The purpose of this FOA is to renew the IBDGC to continue the discovery of susceptibility variants, and to integrate genomic with epigenomic, transcriptomic, proteomic, metabolomic, and other -omic methodologies to elucidate the effects of genetic risk variants on the pathophysiology of IBD.The GRCs will serve as sites of enrollment of IBD patients, relatives, and healthy controls for these studies, and for laboratory-based studies on biological samples taken from these subjects.The PD(s)/PI(s) of the GRCs will serve as members of the Steering Committee of the IBDGC, which will be responsible for all of the IBDGC’s operational decisions, which will be binding upon all of the IBDGC’s members. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-11-032.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.847 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00096811 | Mar 30, 2012 | Apr 30, 2012 | View |
Package 1
Mandatory forms
143254 RR_SF424_1_2-1.2.pdf
143254 PerformanceSite_1_4-1.4.pdf
143254 RR_OtherProjectInfo_1_3-1.3.pdf
143254 RR_KeyPersonExpanded_1_2-1.2.pdf
143254 PHS398_CoverPageSupplement_1_4-1.4.pdf
143254 PHS398_ResearchPlan_1_3-1.3.pdf
143254 PHS398_Checklist_1_3-1.3.pdf
Optional forms
143254 RR_SubawardBudget30-1.2.pdf
143254 PHS398_ModularBudget_1_2-1.2.pdf
143254 RR_Budget-1.1.pdf
143254 PHS_CoverLetter_1_2-1.2.pdf
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