This grant, offered by the National Institute of Environmental Health Sciences (NIEHS), aims to advance our understanding of how environmental chemical exposures contribute to the development of obesity, type 2 diabetes, and metabolic syndrome. Applicants must demonstrate a clear link between specific environmental exposures and increased disease incidence, utilizing either animal models or human studies. While all exposure windows are considered, research focusing on developmental stages—such as in utero, neonatal, or early childhood—is particularly encouraged due to their potential sensitivity. Human studies should connect developmental exposures to early disease biomarkers, whereas animal studies should identify novel chemicals that induce metabolic alterations consistent with these conditions.
Opportunity ID: 170174
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-12-184 |
| Funding Opportunity Title: | Role of Environmental Chemical Exposures in the Development of Obesity, Type 2 Diabetes and Metabolic Syndrome (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 11, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2015 |
| Current Closing Date for Applications: | Sep 07, 2015 |
| Archive Date: | Oct 08, 2015 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Special district governments Small businesses Independent school districts Public housing authorities/Indian housing authorities County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA), issued by the National Institute of Environmental Health Sciences (NIEHS), encourages grant applications to understand the role of environmental chemical exposures in the development of obesity, type 2 diabetes and/or metabolic syndrome. Applications must link an environmental exposure to the increased incidence of weight gain, type 2 diabetes and aspects of metabolic syndrome in animal models or human studies. While any exposure window is acceptable it is anticipated that the most sensitive time for exposures to affect the disease outcomes will be during development e.g., in utero and/or neonatal or early childhood. For human studies developmental exposures (in utero and early childhood) should be linked to early biomarkers of disease onset. Animal studies should focus on identifying new environmental chemicals that alter weight gain, insulin sensitivity and glucose tolerance and altered lipid metabolism indicative of obesity, type 2 diabetes and/or metabolic syndrome. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-12-184.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00121310 | Sep 16, 2012 | Sep 24, 2013 | View | |
| FORMS-C | Use for due dates after 9/24/2013 | PKG00181586 | Sep 16, 2013 | Sep 07, 2015 | View |
Package 1
Mandatory forms
170174 RR_SF424_1_2-1.2.pdf
170174 PerformanceSite_1_4-1.4.pdf
170174 RR_OtherProjectInfo_1_3-1.3.pdf
170174 RR_KeyPersonExpanded_1_2-1.2.pdf
170174 PHS398_CoverPageSupplement_1_4-1.4.pdf
170174 PHS398_ResearchPlan_1_3-1.3.pdf
170174 PHS398_Checklist_1_3-1.3.pdf
Optional forms
170174 RR_SubawardBudget30-1.2.pdf
170174 PHS398_ModularBudget_1_2-1.2.pdf
170174 RR_Budget-1.1.pdf
170174 PHS_CoverLetter_1_2-1.2.pdf
Package 2
Mandatory forms
170174 RR_SF424_2_0-2.0.pdf
170174 PHS398_ResearchPlan_2_0-2.0.pdf
170174 PHS398_CoverPageSupplement_2_0-2.0.pdf
170174 RR_KeyPersonExpanded_2_0-2.0.pdf
170174 RR_OtherProjectInfo_1_3-1.3.pdf
170174 PerformanceSite_2_0-2.0.pdf
Optional forms
170174 RR_SubawardBudget30_1_3-1.3.pdf
170174 PlannedReport-1.0.pdf
170174 PHS398_CumulativeInclusionReport-1.0.pdf
170174 PHS398_ModularBudget_1_2-1.2.pdf
170174 RR_Budget_1_3-1.3.pdf
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