This grant, offered by the National Institute of General Medical Sciences (NIGMS) and several partner NIH institutes, aims to advance the structural biology of membrane proteins. Its purpose is to enhance the rate of membrane protein structure determination and resolve specific, biologically significant structures. The program encourages innovative methods for expression, purification, characterization, and stabilization. Research utilizing X-ray diffraction, NMR, electron microscopy, and mass spectrometry for structural determination is sought. Projects should focus on approaches leading to near-term determination of important membrane protein structures for understanding function. This FOA helps NIH track progress in this vital area.
Opportunity ID: 55732
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-10-228 |
| Funding Opportunity Title: | Structural Biology of Membrane Proteins (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Environment Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 09, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2013 |
| Current Closing Date for Applications: | Sep 07, 2013 |
| Archive Date: | Oct 08, 2013 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities City or township governments Independent school districts Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by NIGMS, as well as NCI, NIA, NIDCD, NIDDK, NIDA, NIEHS and NHLBI, National institutes of Health, encourages grant applications from institutions/organizations that propose to develop research and methods to enhance the rate of membrane protein structure determination and to determine specific membrane protein structures. Innovative methods for expression, oligomerization, solubilization, stabilization, purification, characterization, crystallization, isotopic labeling, and structure determination of unique and biologically significant membrane proteins by x-ray diffraction, nuclear magnetic resonance (NMR), electron microscopy, mass spectrometry, and other biophysical techniques are encouraged. Projects that will lead in the near term to determining the structures of biologically important membrane proteins are also encouraged. Responding to this FOA, rather than the regular investigator-initiated Research Project Grant (R01) FOA, will help NIH staff track interest and progress of research in this scientific area. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-10-228.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00021898 | Oct 14, 2010 | Sep 07, 2013 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00019639 | Sep 05, 2010 | Oct 14, 2010 | View |
Package 1
Mandatory forms
55732 RR_SF424_1_2-1.2.pdf
55732 RR_OtherProjectInfo_1_3-1.3.pdf
55732 RR_KeyPersonExpanded_1_2-1.2.pdf
55732 PerformanceSite_1_4-1.4.pdf
55732 PHS398_ResearchPlan_1_3-1.3.pdf
55732 PHS398_CoverPageSupplement_1_4-1.4.pdf
55732 PHS398_Checklist_1_3-1.3.pdf
Optional forms
55732 RR_Budget-1.1.pdf
55732 RR_SubawardBudget-1.2.pdf
55732 PHS_CoverLetter_1_2-1.2.pdf
55732 PHS398_ModularBudget-1.1.pdf
Package 2
Mandatory forms
55732 RR_SF424_1_2-1.2.pdf
55732 PerformanceSite_1_3-1.3.pdf
55732 RR_OtherProjectInfo_1_2-1.2.pdf
55732 RR_KeyPersonExpanded_1_2-1.2.pdf
55732 PHS398_CoverPageSupplement_1_4-1.4.pdf
55732 PHS398_ResearchPlan_1_3-1.3.pdf
55732 PHS398_Checklist_1_3-1.3.pdf
Optional forms
55732 PHS_CoverLetter_1_2-1.2.pdf
55732 PHS398_ModularBudget-1.1.pdf
55732 RR_Budget-1.1.pdf
55732 RR_SubawardBudget-1.2.pdf
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