The National Institutes of Health is offering a grant to advance research on immune system plasticity in dental, oral, and craniofacial (DOC) diseases. This grant aims to explore mechanisms influencing the immune system’s ability to respond to various disturbances, with the goal of developing personalized therapies that promote regeneration over degeneration. By uncovering new insights, this funding opportunity seeks to revolutionize disease management strategies for DOC conditions across different stages of life.
Opportunity ID: 312404
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-19-173 |
| Funding Opportunity Title: | Achieving Tissue Robustness Through Harnessing Immune System Plasticity (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 29, 2019 |
| Last Updated Date: | Jan 29, 2019 |
| Original Closing Date for Applications: | May 07, 2022 |
| Current Closing Date for Applications: | May 07, 2022 |
| Archive Date: | Jun 12, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Private institutions of higher education Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses County governments Special district governments Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity announcement (FOA) encourages state-of-the-art, systematic research approaches to elucidate the role of immune system plasticity in health and in the pathogenesis of dental, oral, and craniofacial (DOC) diseases. This FOA solicits applications that will seek to determine mechanisms underlying the ability or inability of the immune system to dynamically maintain its functional role against internal and external perturbations. The expectation is that new knowledge derived from this research will facilitate development of novel, personalized immunomodulatory-based therapies that shift the balance between degenerative and regenerative processes toward regeneration disease management in a patient-specific manner across the lifespan. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-19-173.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 312404 Full Announcement-PAR-19-173 -> PAR-19-173-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00247916 | May 16, 2019 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00259789 | May 16, 2019 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270254 | Nov 16, 2021 | May 07, 2022 | View |
Package 1
Mandatory forms
312404 RR_SF424_2_0-2.0.pdf
312404 PHS398_CoverPageSupplement_4_0-4.0.pdf
312404 RR_OtherProjectInfo_1_4-1.4.pdf
312404 PerformanceSite_2_0-2.0.pdf
312404 RR_KeyPersonExpanded_2_0-2.0.pdf
312404 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
312404 RR_Budget_1_4-1.4.pdf
312404 RR_SubawardBudget30_1_4-1.4.pdf
312404 PHS398_ModularBudget_1_2-1.2.pdf
312404 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
312404 RR_SF424_2_0-2.0.pdf
312404 PHS398_CoverPageSupplement_5_0-5.0.pdf
312404 RR_OtherProjectInfo_1_4-1.4.pdf
312404 PerformanceSite_2_0-2.0.pdf
312404 RR_KeyPersonExpanded_2_0-2.0.pdf
312404 PHS398_ResearchPlan_4_0-4.0.pdf
312404 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
312404 RR_Budget_1_4-1.4.pdf
312404 RR_SubawardBudget30_1_4-1.4.pdf
312404 PHS398_ModularBudget_1_2-1.2.pdf
312404 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
312404 RR_SF424_5_0-5.0.pdf
312404 PHS398_CoverPageSupplement_5_0-5.0.pdf
312404 RR_OtherProjectInfo_1_4-1.4.pdf
312404 PerformanceSite_4_0-4.0.pdf
312404 RR_KeyPersonExpanded_4_0-4.0.pdf
312404 PHS398_ResearchPlan_4_0-4.0.pdf
312404 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
312404 RR_Budget_3_0-3.0.pdf
312404 RR_SubawardBudget30_3_0-3.0.pdf
312404 PHS398_ModularBudget_1_2-1.2.pdf
312404 PHS_AssignmentRequestForm_3_0-3.0.pdf
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