This NIH grant focuses on developing scalable technologies to investigate the poorly understood protein classes in the Druggable Genome, emphasizing functional studies at molecular and cellular levels in a high-throughput manner. The aim is to establish efficient technology platforms and experimental workflows for comprehensive exploration of un-annotated proteins encoded by the Druggable Genome. Applications should propose innovative approaches to accelerate the characterization of these proteins through scalable technology adaptation. Closing date for submissions is December 11, 2013.
Opportunity ID: 242773
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-RM-13-010 |
| Funding Opportunity Title:: | Adaptation of Scalable Technologies to Illuminate the Druggable Genome (U01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Sep 16, 2013 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Dec 11, 2013 |
| Current Closing Date for Applications:: | Dec 11, 2013 |
| Archive Date:: | Jan 11, 2014 |
| Estimated Total Program Funding:: | $ 2,500,000 |
| Award Ceiling:: | $275,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The overarching goals of this Funding Opportunity Announcement (FOA) and the companion announcement (RFA-RM-13-011) are to foster the development of technologies and information management to facilitate the unveiling of the functions of the poorly characterized and/or un-annotated members in four protein classes of the Druggable Genome. This FOA calls for adaptation of an ensemble of scalable technology platforms to characterize functions of proteins as a large group at molecular and cellular levels in medium- to high-throughput fashion, rather than repeating the one at a time approach that might otherwise be undertaken. The objective is to establish transformative scalable technology platforms and streamlined experimental workflows incorporated with multiple robust assay and physiological perturbation protocols for large-scale functional studies of poorly characterized and/or un-annotated proteins encoded by the Druggable Genome. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.310 |
| Competition ID: | FORMS-C |
| Competition Title: | Forms-C |
| Opportunity Package ID: | PKG00185290 |
| Opening Date: | Nov 11, 2013 |
| Closing Date: | Dec 11, 2013 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.310 | FORMS-C | Forms-C | PKG00185290 | Nov 11, 2013 | Dec 11, 2013 | View | eRA Commons Help Desk | Organization Applicants |