NIH Blueprint Neurotherapeutics Network Grant: Drug Discovery for Nervous System Disorders

The NIH Blueprint Neurotherapeutics Network Grant supports neuroscience investigators in advancing small molecule drug discovery projects targeting disorders of the nervous system. Funding covers activities in participants’ laboratories and collaboration opportunities with NIH-funded experts and research organizations. Projects can focus on Discovery stage optimization of hit compounds or Development stage advancement of development candidates, including toxicology studies and phase I clinical testing. Successful projects may progress from Discovery to Development stages. Participants retain intellectual property rights to developed drug candidates. Closing date for applications: Mar 09, 2017.

Opportunity ID: 260047

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PAR-14-293
Funding Opportunity Title::	Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (UH2/UH3)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.121 — Oral Diseases and Disorders Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 2
Posted Date::	Jul 22, 2014
Last Updated Date::	Mar 09, 2017
Original Closing Date for Applications::	May 07, 2017
Current Closing Date for Applications::	Mar 09, 2017
Archive Date::	Apr 08, 2017
Estimated Total Program Funding::
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

State governments

Additional Information on Eligibility::

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name::	National Institutes of Health
Description::	The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN receive funding for activities to be conducted in their own laboratories and the opportunity to collaborate with NIH-funded consultants and contract research organizations (CROs) that specialize in medicinal chemistry, pharmacokinetics, toxicology, formulations development, chemical synthesis under Good Manufacturing Practices (GMP), and Phase I clinical testing. Projects can enter either at the Discovery stage, to optimize well-validated hit compounds through medicinal chemistry, or at the Development stage, to advance development candidates through Investigational New Drug (IND)-enabling toxicology studies and phase I clinical testing. Projects that enter at the Discovery stage and meet their milestones may continue on through Development. BPN participants receive intellectual property rights to drug candidates developed through the program.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 2	Expired and Re-issued as PAR-17-205	Mar 09, 2017
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	FORMS-C
Competition Title:	FORMS-C
Opportunity Package ID:	PKG00201517
Opening Date:	Sep 21, 2014
Closing Date:	Jun 07, 2016
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research & Related Budget [V1.3] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3]

Package No: 2