The NIH Blueprint Neurotherapeutics Network Grant supports neuroscience investigators in advancing small molecule drug discovery projects targeting disorders of the nervous system. Funding covers activities in participants’ laboratories and collaboration opportunities with NIH-funded experts and research organizations. Projects can focus on Discovery stage optimization of hit compounds or Development stage advancement of development candidates, including toxicology studies and phase I clinical testing. Successful projects may progress from Discovery to Development stages. Participants retain intellectual property rights to developed drug candidates. Closing date for applications: Mar 09, 2017.
Opportunity ID: 260047
General Information
Document Type:: | Grants Notice |
Funding Opportunity Number:: | PAR-14-293 |
Funding Opportunity Title:: | Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (UH2/UH3) |
Opportunity Category:: | Discretionary |
Opportunity Category Explanation:: | |
Funding Instrument Type:: | |
Category of Funding Activity:: | Education |
Category Explanation:: | |
Expected Number of Awards:: | |
Assistance Listings Number(s):: | 93.121 — Oral Diseases and Disorders Research |
Cost Sharing or Matching Requirement:: | No |
Version:: | Synopsis 2 |
Posted Date:: | Jul 22, 2014 |
Last Updated Date:: | Mar 09, 2017 |
Original Closing Date for Applications:: | May 07, 2017 |
Current Closing Date for Applications:: | Mar 09, 2017 |
Archive Date:: | Apr 08, 2017 |
Estimated Total Program Funding:: | |
Award Ceiling:: | $ |
Award Floor:: | $ |
Eligibility
Eligible Applicants:: | State governments |
Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
Agency Name:: | National Institutes of Health |
Description:: | The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN receive funding for activities to be conducted in their own laboratories and the opportunity to collaborate with NIH-funded consultants and contract research organizations (CROs) that specialize in medicinal chemistry, pharmacokinetics, toxicology, formulations development, chemical synthesis under Good Manufacturing Practices (GMP), and Phase I clinical testing. Projects can enter either at the Discovery stage, to optimize well-validated hit compounds through medicinal chemistry, or at the Development stage, to advance development candidates through Investigational New Drug (IND)-enabling toxicology studies and phase I clinical testing. Projects that enter at the Discovery stage and meet their milestones may continue on through Development. BPN participants receive intellectual property rights to drug candidates developed through the program. |
Link to Additional Information:: | |
Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
Version | Modification Description | Updated Date |
---|---|---|
Synopsis 2 | Expired and Re-issued as PAR-17-205 | Mar 09, 2017 |
Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
Assistance Listings: | |
Competition ID: | FORMS-C |
Competition Title: | FORMS-C |
Opportunity Package ID: | PKG00201517 |
Opening Date: | Sep 21, 2014 |
Closing Date: | Jun 07, 2016 |
Agency Contact Information:: | eRA Commons Help Desk |
Who Can Apply:: | Organization Applicants |
mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research & Related Budget [V1.3] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
optional_forms |
Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] |
Package No: 2
Assistance Listings: | |
Competition ID: | FORMS-D |
Competition Title: | Use for due dates on or after May 25, 2016 |
Opportunity Package ID: | PKG00223993 |
Opening Date: | Jul 11, 2016 |
Closing Date: | Mar 10, 2017 |
Agency Contact Information:: | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ |
Who Can Apply:: | Organization Applicants |
mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Cover Page Supplement [V3.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research & Related Budget [V1.3] PHS 398 Research Plan [V3.0] |
optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] PHS Inclusion Enrollment Report [V1.0] PHS Assignment Request Form [V1.0] |
Packages
Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
---|---|---|---|---|---|---|---|---|
FORMS-C | FORMS-C | PKG00201517 | Sep 21, 2014 | Jun 07, 2016 | View | eRA Commons Help Desk | Organization Applicants |
Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
---|---|---|---|---|---|---|---|---|
FORMS-D | Use for due dates on or after May 25, 2016 | PKG00223993 | Jul 11, 2016 | Mar 10, 2017 | View | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ | Organization Applicants |