Opportunity ID: 272449

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-EY-15-001
Funding Opportunity Title: Brain Initiative: New Concepts and Early-Stage Research for Large-Scale Recording and Modulation in the Nervous System (R21)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 15
Assistance Listings: 93.867 — Vision Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Jan 30, 2015
Last Updated Date:
Original Closing Date for Applications: Apr 16, 2015
Current Closing Date for Applications: Apr 16, 2015
Archive Date: May 17, 2015
Estimated Total Program Funding: $6,000,000
Award Ceiling: $200,000
Award Floor:

Eligibility

Eligible Applicants: State governments
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Special district governments
County governments
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Small businesses
Public and State controlled institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: A central goal of the BRAIN Initiative is to understand how electrical and chemical signals code information in neural circuits and give rise to sensations, thoughts, emotions and actions. Available technologies for recording and manipulating neural circuit activity in human and animal experiments are not sufficient to accomplish this goal. Non-invasive technologies are low resolution and/or provide indirect measures such as blood flow, which are imprecise. Invasive technologies can provide information at the level of single neurons producing the fundamental biophysical signals, but they can only be applied to tens or hundreds of neurons, out of a total number in the human brain estimated at 85 billion.

Previous BRAIN FOAs sought to develop novel technology (RFA-NS-15-003) or to optimize existing technology ready for in-vivo proof-of-concept testing and collection of preliminary data (RFA-NS-15-004). This FOA seeks applications for technology at an even earlier stage of development. It seeks new and untested ideas that are in the very earliest stages.

The support provided might enable calculations, simulations, computational models, or other mathematical approaches for demonstrating that the signal sources and/or measurement technologies are theoretically capable of meeting the demands of large-scale recording or manipulation of circuit activity. The support might also be used for building and testing phantoms, prototypes, in-vitro or other bench-top models in order to validate underlying theoretical assumptions in preparation for future FOAs aimed at testing in animal models.

Invasive or non-invasive approaches are sought that will ultimately enable or reduce the current barriers to large-scale recording or manipulation of neural activity, and that would be compatible with experiments in humans or behaving animals. Applications are encouraged from any qualified individuals, including physicists, engineers, theoreticians, and scientists, especially those not typically involved with neuroscience research.

Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-EY-15-001.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email:FBOWebmaster@OD.NIH.GOV

Version History

Version Modification Description Updated Date

Related Documents

Packages

Agency Contact Information: NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email: FBOWebmaster@OD.NIH.GOV

Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-C FORMS-C PKG00212785 Mar 16, 2015 Apr 16, 2015 View

Package 1

Mandatory forms

272449 RR_SF424_2_0-2.0.pdf

272449 PHS398_ResearchPlan_2_0-2.0.pdf

272449 PHS398_CoverPageSupplement_2_0-2.0.pdf

272449 RR_KeyPersonExpanded_2_0-2.0.pdf

272449 RR_OtherProjectInfo_1_3-1.3.pdf

272449 PerformanceSite_2_0-2.0.pdf

Optional forms

272449 RR_SubawardBudget30_1_3-1.3.pdf

272449 PlannedReport-1.0.pdf

272449 PHS398_CumulativeInclusionReport-1.0.pdf

272449 PHS398_ModularBudget_1_2-1.2.pdf

272449 RR_Budget_1_3-1.3.pdf

2025-07-09T08:45:59-05:00

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