The National Institutes of Health (NIH) is offering grants as part of the BRAIN Initiative to support the development of tools and resources for analyzing brain microconnectivity. The goal is to create novel techniques that will be widely available for studying microconnectivity in healthy and diseased brains of model organisms and humans. The emphasis is on reducing costs, improving mapping capabilities, and overcoming technical barriers in electron microscopy and super resolution light microscopic approaches. Applicants are encouraged to provide proof-of-principle demonstrations, reference datasets, and enhanced automation for neuronal structure segmentation and analysis in EM images. Applications are due by November 13, 2018.
Opportunity ID: 296951
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-MH-18-505 |
| Funding Opportunity Title: | BRAIN Initiative: Tools to Facilitate High-Throughput Microconnectivity Analysis (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 30, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 13, 2018 |
| Current Closing Date for Applications: | Nov 13, 2018 |
| Archive Date: | Dec 19, 2018 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) Special district governments City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Private institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate tools and resources to facilitate the detailed analysis of brain microconnectivity. Novel and augmented techniques are sought that will ultimately be broadly accessible to the neuroscience community for the interrogation of microconnectivity in healthy and diseased brains of model organisms and humans. Development of technologies that will significantly drive down the cost of connectomics would enable routine mapping of the microconnectivity on the same individuals that have been analyzed physiologically, or to compare normal and pathological tissues in substantial numbers of multiple individuals to assess variability. Advancements in both electron microscopy (EM) and super resolution light microscopic approaches are sought. Applications that propose to develop approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged. Proof-of-principle demonstrations and/or reference datasets enabling future development are welcome, as are improved approaches for automated segmentation and analysis strategies of neuronal structures in EM images. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-18-505.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or before January 24, 2018 | PKG00234523 | Nov 07, 2017 | Jan 24, 2018 | View | |
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00236013 | Nov 09, 2017 | Nov 13, 2018 | View |
Package 1
Mandatory forms
296951 RR_SF424_2_0-2.0.pdf
296951 PHS398_CoverPageSupplement_3_0-3.0.pdf
296951 RR_OtherProjectInfo_1_3-1.3.pdf
296951 PerformanceSite_2_0-2.0.pdf
296951 RR_KeyPersonExpanded_2_0-2.0.pdf
296951 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
296951 RR_Budget_1_3-1.3.pdf
296951 RR_SubawardBudget30_1_3-1.3.pdf
296951 PHS398_ModularBudget_1_2-1.2.pdf
296951 PHS_Inclusion_Enrollment_Report-1.0.pdf
296951 PHS_AssignmentRequestForm-1.0.pdf
Package 2
Mandatory forms
296951 RR_SF424_2_0-2.0.pdf
296951 PHS398_CoverPageSupplement_4_0-4.0.pdf
296951 RR_OtherProjectInfo_1_4-1.4.pdf
296951 PerformanceSite_2_0-2.0.pdf
296951 RR_KeyPersonExpanded_2_0-2.0.pdf
296951 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
296951 RR_Budget_1_4-1.4.pdf
296951 RR_SubawardBudget30_1_4-1.4.pdf
296951 PHS398_ModularBudget_1_2-1.2.pdf
296951 PHS_AssignmentRequestForm_2_0-2.0.pdf
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