This NIH BRAIN Initiative grant supports Comprehensive Centers to develop and test scalable technologies for creating brain-wide atlases of mouse circuit connectivity. The funding aims to establish robust data collection, analysis, and dissemination pipelines, demonstrating cell-to-cell connectivity at synaptic resolution. Awardees will validate their approach in chosen CNS sub-volumes by testing structure-function hypotheses. Centers must also incorporate tools for integrating diverse data and enabling community interaction with the data. These centers will join the BRAIN CONNECTS Network, a coordinated effort to develop complete brain wiring diagrams across multiple scales.
Opportunity ID: 338249
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-22-048 |
| Funding Opportunity Title: | BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Comprehensive Centers for Mouse Brain (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 22, 2022 |
| Last Updated Date: | Feb 22, 2022 |
| Original Closing Date for Applications: | Jun 13, 2023 |
| Current Closing Date for Applications: | Jun 13, 2023 |
| Archive Date: | Jul 19, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments City or township governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Private institutions of higher education County governments State governments Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) supports Comprehensive Centers to develop and test technologies that can be scaled to brain-wide atlases of mouse circuit connectivity. Centers will establish data collection, analysis, and dissemination pipelines to demonstrate the feasibility of mapping cell-to-cell connectivity with a minimum resolution of synaptic connections. They will demonstrate the significance of the approach within the context of a chosen CNS sub-volume, by testing specific hypotheses relating circuit structure to function. They will also incorporate toolsets and infrastructure for integrating separately collected data from smaller volumes, as well as from other data collection modalities, and for enabling the neuroscience community to interact with and mine the data for new research questions. Centers will be integrated into the BRAIN CONNECTS Network, consisting of projects from this FOA and its companion announcements, as a coordinated effort aimed at developing wiring diagrams that can span entire brains across multiple scales. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-048.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 338249 Full Announcement-RFA-NS-22-048 -> RFA-NS-22-048-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00272171 | Jun 13, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278476 | Nov 15, 2022 | Jun 13, 2023 | View |
Package 1
Mandatory forms
338249 RR_SF424_5_0-5.0.pdf
338249 PHS398_CoverPageSupplement_5_0-5.0.pdf
338249 RR_OtherProjectInfo_1_4-1.4.pdf
338249 PerformanceSite_4_0-4.0.pdf
338249 RR_KeyPersonExpanded_4_0-4.0.pdf
338249 RR_Budget_3_0-3.0.pdf
338249 PHS398_ResearchPlan_4_0-4.0.pdf
338249 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338249 RR_SubawardBudget30_3_0-3.0.pdf
338249 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
338249 RR_SF424_5_0-5.0.pdf
338249 PHS398_CoverPageSupplement_5_0-5.0.pdf
338249 RR_OtherProjectInfo_1_4-1.4.pdf
338249 PerformanceSite_4_0-4.0.pdf
338249 RR_KeyPersonExpanded_4_0-4.0.pdf
338249 RR_Budget_3_0-3.0.pdf
338249 PHS398_ResearchPlan_5_0-5.0.pdf
338249 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338249 RR_SubawardBudget30_3_0-3.0.pdf
338249 PHS_AssignmentRequestForm_3_0-3.0.pdf
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