NIH BRAIN Initiative: Novel Tools for Brain Cell-Specific Analysis and Circuit Processes (U01)

The National Institutes of Health (NIH) is offering the BRAIN Initiative grant to develop advanced tools for analyzing cell-specific and circuit-specific processes in the brain. The focus is on creating innovative technologies that provide detailed insights into complex neural circuits and cellular interactions underlying brain function. Emphasis is on tools with high specificity at the cellular or circuit level, particularly in delivering genes, proteins, and chemicals to target cells. Proposals should overcome technical limitations, offer validations of tool utility, and enhance precision and sensitivity in targeting specific cell types or circuits in the nervous system. Projects with multi-species applicability are highly favored.

Opportunity ID: 249302

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-MH-14-216
Funding Opportunity Title::	BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit Specific Processes in the Brain (U01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.113 — Environmental Health
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Dec 17, 2013
Last Updated Date::
Original Closing Date for Applications::	Mar 13, 2014
Current Closing Date for Applications::	Mar 13, 2014
Archive Date::	Apr 13, 2014
Estimated Total Program Funding::	$ 5,000,000
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

State governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should confer a high degree of cell-type and/or circuit-level specificity. Validation of the utility of the tool/technology is an essential feature. A particular emphasis for this funding opportunity announcement (FOA) is the development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest; new approaches are also expected to target specific cell types and or circuits in the nervous system with greater precision and sensitivity than currently established methods. Tools developed through this initiative that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are also encouraged.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00191115
Opening Date:	Feb 13, 2014
Closing Date:	Mar 13, 2014
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3]