This grant, offered by the NIH Common Fund Protein Capture Initiative, represents the initial phase of a pilot program to establish a comprehensive community resource of high-quality, renewable affinity reagents for all human proteins. It specifically invites projects focused on the production of targeted human proteins or peptides. These immunogens are intended for generating monoclonal antibodies, valuable for immunoprecipitation studies and other applications. The produced proteins/peptides will be made available as a renewable resource, such as clones or transfected cell lines, for the wider scientific community. The initiative prioritizes human transcription factors as the initial set of targets, aiming to significantly advance protein research and accessibility.
Opportunity ID: 52202
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-10-007 |
| Funding Opportunity Title: | Production Of Human Proteins To Be Used For Generating Affinity Reagents (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 26, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 26, 2010 |
| Current Closing Date for Applications: | Apr 26, 2010 |
| Archive Date: | May 27, 2010 |
| Estimated Total Program Funding: | $1,000,000 |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Private institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA is the first component of a pilot program organized under the NIH Common Fund Protein Capture Initiative to examine the feasibility and value of generating a community resource of high quality, renewable affinity reagents for all human proteins. This specific FOA topic is focused on the production of proteins or peptides for the purpose of generating monoclonal antibodies that can be used in immunoprecipitation studies, and potentially for other affinity reagents, as well as broader uses by the scientific community and others. Thus, the FOA solicits projects that will provide the targeted proteins, peptides or other immunogens to other components of the pilot program (including a component that will generate monoclonal antibodies, to be solicited in FY2011), as well as to the wider community in the form of a renewable resource, e.g., clones or transfected cell lines.This FOA will prioritize human transcription factors as an initial set of targets.
Mechanism of Support. This FOA will utilize the U01 Research Project Cooperative Agreement activity code. Funds Available and Anticipated Number of Awards..We expect to fund a single three year award in FY2010. Total funds available for the program are $1M, for each of three years.. Budget and Project Period.Applications should propose no more than $600,000 in direct costs per year over a period of no more than three years. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-007.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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