The NIH is offering the CounterACT Basic Research Grant to support projects investigating chemical threats that impact the nervous system. This grant focuses on agents like chemical warfare compounds, toxic industrial chemicals, and pesticides. These threats pose risks through potential terrorist attacks or accidental industrial releases. Funded research is expected to significantly advance our understanding of these agents’ toxicity mechanisms, uncover new effects from exposure, and identify novel targets for therapeutic interventions. This initiative aims to generate crucial data for developing effective countermeasures against neurotoxic chemical threats, ultimately enhancing public health preparedness and response capabilities for chemical emergencies.
Opportunity ID: 356935
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-077 |
| Funding Opportunity Title: | CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 4 |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 01, 2024 |
| Last Updated Date: | Nov 01, 2024 |
| Original Closing Date for Applications: | Oct 16, 2026 |
| Current Closing Date for Applications: | Oct 16, 2026 |
| Archive Date: | Nov 21, 2026 |
| Estimated Total Program Funding: | $300,000 |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Independent school districts Small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This announcement invites applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pesticides that have primary or secondary effects on the nervous system. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. Projects supported by this NOFO are expected to generate data that elucidate mechanisms of toxicity of these agents, possible new manifestations of toxic exposures, and potential new targets for therapeutic development. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-077.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356935 Full Announcement-PAR-25-077 -> PAR-25-077-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288360 | Sep 17, 2025 | Oct 16, 2026 | View |
Package 1
Mandatory forms
356935 RR_SF424_5_0-5.0.pdf
356935 PHS398_CoverPageSupplement_5_0-5.0.pdf
356935 RR_OtherProjectInfo_1_4-1.4.pdf
356935 PerformanceSite_4_0-4.0.pdf
356935 RR_KeyPersonExpanded_4_0-4.0.pdf
356935 PHS398_ResearchPlan_5_0-5.0.pdf
356935 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356935 RR_Budget_3_0-3.0.pdf
356935 RR_SubawardBudget30_3_0-3.0.pdf
356935 PHS398_ModularBudget_1_2-1.2.pdf
356935 PHS_AssignmentRequestForm_4_0-4.0.pdf
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