The National Cancer Institute (NCI), National Institute on Alcohol Abuse and Alcoholism (NIAAA), and Office of Dietary Supplements (ODS) are offering this R01 grant to promote clinical and preclinical research. This grant is for investigating how diet and dietary factors, including supplements, influence DNA methylation, histone posttranslational modification, noncoding RNA, and other epigenetic processes crucial for cancer prevention and development. A key purpose is to foster collaborations between nutrition and epigenetic experts. Projects should examine bioactive food components with cancer-preventative properties and analyze key epigenetic events like carcinogen metabolism and cell division, aiming to establish clear links between epigenetics, methylation patterns, and tumor incidences or behaviors.
Opportunity ID: 48480
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-234 |
| Funding Opportunity Title: | Diet, Epigenetic Events, and Cancer Prevention (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 15, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2012 |
| Current Closing Date for Applications: | Sep 07, 2012 |
| Archive Date: | Oct 08, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses For profit organizations other than small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities State governments Special district governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. The aim of this funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the Office of Dietary Supplements (ODS), of the National Institutes of Health (NIH), is to promote clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttranslational modification, noncoding RNA, and other epigenetic processes involved in cancer prevention and development. Another important aim of this FOA is to encourage collaborations between nutrition and epigenetic experts to study bioactive food components with cancer-preventative properties and to examine key epigenetic events in cancer processes (e.g., carcinogen metabolism, cell division, differentiation, and apoptosis) in order to begin to establish linkages between epigenetics, methylation patterns, and tumor incidences/behaviors. Mechanism of Support. This FOA uses the NIH research project R01 grant mechanism and runs in parallel with an FOA of identical scientific scope, PA-09-235 that encourages applications under the NIH Exploratory/Developmental (R21) Grant mechanism. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-234.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00014707 | Dec 21, 2009 | Oct 13, 2010 | View | |
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00021817 | Oct 13, 2010 | Sep 07, 2012 | View | |
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00013089 | Sep 05, 2009 | Feb 20, 2010 | View |
Package 1
Mandatory forms
48480 RR_SF424_1_2-1.2.pdf
48480 PerformanceSite_1_3-1.3.pdf
48480 RR_OtherProjectInfo_1_2-1.2.pdf
48480 RR_KeyPersonExpanded_1_2-1.2.pdf
48480 PHS398_CoverPageSupplement_1_4-1.4.pdf
48480 PHS398_ResearchPlan_1_3-1.3.pdf
48480 PHS398_Checklist_1_3-1.3.pdf
Optional forms
48480 PHS_CoverLetter_1_2-1.2.pdf
48480 PHS398_ModularBudget-1.1.pdf
48480 RR_Budget-1.1.pdf
48480 RR_SubawardBudget-1.2.pdf
Package 2
Mandatory forms
48480 RR_SF424_1_2-1.2.pdf
48480 RR_OtherProjectInfo_1_3-1.3.pdf
48480 RR_KeyPersonExpanded_1_2-1.2.pdf
48480 PerformanceSite_1_4-1.4.pdf
48480 PHS398_ResearchPlan_1_3-1.3.pdf
48480 PHS398_CoverPageSupplement_1_4-1.4.pdf
48480 PHS398_Checklist_1_3-1.3.pdf
Optional forms
48480 RR_Budget-1.1.pdf
48480 RR_SubawardBudget-1.2.pdf
48480 PHS_CoverLetter_1_2-1.2.pdf
48480 PHS398_ModularBudget-1.1.pdf
Package 3
Mandatory forms
48480 RR_SF424-1.1.pdf
48480 RR_KeyPersonExpanded-1.1.pdf
48480 RR_OtherProjectInfo-1.1.pdf
48480 RR_PerformanceSite-1.1.pdf
48480 PHS398_CoverPageSupplement-1.1.pdf
48480 PHS398_ResearchPlan-1.1.pdf
48480 PHS398_Checklist-1.1.pdf
Optional forms
48480 PHS398_CoverLetter-1.1.pdf
48480 PHS398_ModularBudget-1.1.pdf
48480 RR_Budget-1.1.pdf
48480 RR_SubawardBudget-1.2.pdf
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