The NIH Directors Transformative Research Award supports individual or group scientists proposing groundbreaking, exceptionally innovative research. This grant aims to create new scientific paradigms, establish improved clinical approaches, or develop transformative technologies. Applications are strongly encouraged from diverse backgrounds, including underrepresented groups, and from all eligible institutions across relevant NIH topic areas. No preliminary data are required; projects must demonstrate compelling potential for major impact. As part of NIH’s High-Risk, High-Reward Research program, this award employs an anonymized peer review process to ensure funding for the most impactful and unconventional scientific proposals.
Opportunity ID: 347164
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-23-006 |
| Funding Opportunity Title: | NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 28, 2023 |
| Last Updated Date: | Mar 28, 2023 |
| Original Closing Date for Applications: | Sep 01, 2023 |
| Current Closing Date for Applications: | Sep 01, 2023 |
| Archive Date: | Oct 07, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities State governments City or township governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Small businesses County governments Independent school districts Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIH Directors Transformative Research Award Program supports individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups (see, Notice of NIH’s Interest in Diversity, NOT-OD-20-031) are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications are welcome from the full spectrum of eligible institutions in all geographic locations and in all topic areas relevant to the broad mission of NIH, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Directors Transformative Research Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund. Towards the objective of funding the best possible science, the Office of Strategic Coordination and the Center for Scientific Review are piloting a process for initial peer review of applications received in response to this FOA in which the identity of the investigators and institutions are withheld until the last phase of review. Instructions for anonymizing components of the application are given in Section IV and must be carefully followed. A description of the review process is given in Section V. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-23-006.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 347164 Full Announcement-RFA-RM-23-006 -> RFA-RM-23-006-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00280849 | Aug 01, 2023 | Sep 01, 2023 | View |
Package 1
Mandatory forms
347164 RR_SF424_5_0-5.0.pdf
347164 PHS398_CoverPageSupplement_5_0-5.0.pdf
347164 RR_OtherProjectInfo_1_4-1.4.pdf
347164 PerformanceSite_4_0-4.0.pdf
347164 RR_KeyPersonExpanded_4_0-4.0.pdf
347164 PHS398_ResearchPlan_5_0-5.0.pdf
347164 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
347164 RR_Budget_3_0-3.0.pdf
347164 RR_SubawardBudget30_3_0-3.0.pdf
347164 PHS398_ModularBudget_1_2-1.2.pdf
347164 PHS_AssignmentRequestForm_3_0-3.0.pdf
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