NIH is offering the Drug Docking and Screening Data Resource Grant (U01) to increase publicly available data on protein-drug ligand complexes. This data is crucial for developing and validating drug docking and screening software, which can accelerate drug discovery and lower development costs. The grant aims to enhance the prediction of off-target binding side effects and promote the repurposing of existing pharmaceuticals. Applications are accepted until Nov 01, 2013.
Opportunity ID: 236600
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-GM-14-010 |
| Funding Opportunity Title:: | Drug Docking and Screening Data Resource (U01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | 1 |
| Assistance Listings Number(s):: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Jun 19, 2013 |
| Last Updated Date:: | Oct 18, 2013 |
| Original Closing Date for Applications:: | Oct 09, 2013 |
| Current Closing Date for Applications:: | Nov 01, 2013 |
| Archive Date:: | Dec 01, 2013 |
| Estimated Total Program Funding:: | $ 750,000 |
| Award Ceiling:: | $500,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | City or township governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The purpose of this Funding Opportunity Announcement (FOA) is to continue to increase the amount of publicly available, high-quality data describing structures and affinities of protein-drug ligand complexes -data vital for development, validation, and benchmarking of drug docking and screening software. Accurate and robust methods for in silico drug screening are expected to speed drug discovery and reduce drug development cost by focusing experimental efforts on the most promising candidate compounds. The ability to predict side effects resulting from off-target binding and to increase repurposing of existing pharmaceuticals is an additional expected benefit. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Modified Archive Date based on new Expiration Date, per NOT-OD-14-003. | Oct 18, 2013 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.859 |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates after 9/24/2013 |
| Opportunity Package ID: | PKG00179811 |
| Opening Date: | Sep 09, 2013 |
| Closing Date: | Nov 01, 2013 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| 93.859 | FORMS-C | Use for due dates after 9/24/2013 | PKG00179811 | Sep 09, 2013 | Nov 01, 2013 | View | eRA Commons Help Desk | Organization Applicants |