NIH Grant: Advancing Biomarkers with Extracellular RNA (UH2/UH3)

The National Institutes of Health (NIH) is offering a grant to advance the development of extracellular RNA (exRNA)-based biomarkers from human body fluids for diagnosing and monitoring disease progression and treatment response. This grant aims to establish clinically relevant biomarkers that benefit patients by enhancing their quality of life and survival during clinical trials. Projects should focus on identifying and validating exRNA biomarkers in specific patient groups, introducing new technologies for biomarker monitoring, and creating reliable assays for validated markers. Deadline for applications is November 13, 2012.

Opportunity ID: 189277

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-RM-12-013
Funding Opportunity Title::	Clinical Utility of Extracellular RNA for Biomarker Development (UH2/UH3)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.310 — Trans-NIH Research Support
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Aug 03, 2012
Last Updated Date::
Original Closing Date for Applications::	Nov 13, 2012
Current Closing Date for Applications::	Nov 13, 2012
Archive Date::	Dec 14, 2012
Estimated Total Program Funding::	$ 4,000,000
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Small businesses

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The NIH invites applications for projects that will identify and qualify extracellular RNA (exRNA)-based biomarkers derived from human body fluids, such as blood, saliva, urine, breast milk, amniotic fluid, cerebrospinal fluid, ascites and pleural effusions, in order to diagnose and monitor disease progression and response to therapy. The overall goal of this project is to develop reliable, well-defined and clinically relevant biomarkers derived from extracellular RNA that measure tangible benefits for patients in terms of how they feel, function, and survive in clinical trials. Appropriate studies under this FOA will identify and validate candidate exRNA-based biomarkers in well-defined patient populations, provide new technologies to monitor biomarkers or establish reliable assays for validated markers
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.310
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00136451
Opening Date:	Oct 12, 2012
Closing Date:	Nov 13, 2012
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS Cover Letter [V1.2]