NIH is offering a grant to develop neurophysiological assays as new tools for treatment research in mental disorders. This grant aims to optimize and evaluate measures across species for potential drug and device therapies, identifying discrepancies between animal models and human studies. By enhancing the coherence between preclinical and clinical evaluations, this initiative seeks to expedite the development of more effective treatments for mental disorders. Closing date: Oct 24, 2018.
Opportunity ID: 298915
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-18-268 |
| Funding Opportunity Title: | Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 21, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 24, 2018 |
| Current Closing Date for Applications: | Oct 24, 2018 |
| Archive Date: | Nov 29, 2018 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education Private institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Special district governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The overall goal of this initiative is to identify neurophysiological measures as potential assays for treatment development research. The FOA will support efforts to optimize and evaluate measures of neurophysiological processes that are disrupted within or across mental disorders in both healthy humans and in another species relevant to the therapeutic development pipeline. The initiative will support initial proof of concept studies aimed at identifying measures for potential development as preclinical assays for evaluating potential new drug and device therapies and their targets. Data will also reveal assay measures where the performance between preclinical animal species and humans is dissimilar, thus establishing a firm basis for limiting speculative extrapolations of preclinical animal findings to humans. The ultimate practical goal of this FOA is to improve the efficiency of the therapeutic development process by identifying coherence of measures and inconsistencies between the preclinical screening pipeline and clinical evaluation of new treatment candidates and thereby hasten the development of more effective treatments for mental disorders. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-18-268.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00236476 | Jan 24, 2018 | Oct 24, 2018 | View |
Package 1
Mandatory forms
298915 RR_SF424_2_0-2.0.pdf
298915 PHS398_CoverPageSupplement_4_0-4.0.pdf
298915 RR_OtherProjectInfo_1_4-1.4.pdf
298915 PerformanceSite_2_0-2.0.pdf
298915 RR_KeyPersonExpanded_2_0-2.0.pdf
298915 RR_Budget_1_4-1.4.pdf
298915 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
298915 RR_SubawardBudget30_1_4-1.4.pdf
298915 PHS_AssignmentRequestForm_2_0-2.0.pdf
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