The National Institutes of Health (NIH) is offering this grant to continue essential support for the Pediatric Brain Tumor Consortium (PBTC), a dedicated clinical trials organization. This grant is for the critical purpose of translating innovative therapies from the laboratory into early phase clinical testing, aiming to significantly improve treatment and outcomes for children afflicted with primary brain tumors. The PBTC directly addresses the ongoing challenge of high mortality rates in aggressive pediatric brain tumor types, including DIPG and malignant gliomas, and seeks to reduce long-term functional impediments in survivors. This limited-competition funding ensures the PBTC continues to fulfill its unique role within the NIH’s pediatric brain tumor research portfolio by advancing multiple novel therapies.
Opportunity ID: 236597
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-13-502 |
| Funding Opportunity Title: | Limited Competition: Pediatric Brain Tumor Consortium (UM1) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.395 — Cancer Treatment Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 19, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 16, 2013 |
| Current Closing Date for Applications: | Sep 16, 2013 |
| Archive Date: | Oct 17, 2013 |
| Estimated Total Program Funding: | $2,590,000 |
| Award Ceiling: | $2,590,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Only the current awardees of Pediatric Brain Tumor Consortium funded under RFA-CA-08-026 are eligible to apply under this Limited Competition FOA. Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) is intended to continue support for the Pediatric Brain Tumor Consortium (PBTC). This limited-competition FOA solicits a single application from the current PBTC awardee. The PBTC was conceived as a dedicated clinical trials organization able to translate innovative therapies from the laboratory to early phase clinical testing so that treatment for primary brain tumors in children can be improved. The importance of the PBTC is highlighted by the continuing high mortality rate among some common brain tumor histotypes occurring in children [e.g., diffuse intrinsic pontine gliomas (DIPG), malignant supratentorial gliomas, and biologically high-risk medulloblastomas and ependymomas] and the functional impediments apparent in a large proportion of children surviving current therapies. The PBTC is designed to fill a unique niche in the NIH pediatric brain tumor research portfolio through its ability to translate multiple innovative therapies from the laboratory to early phase clinical testing. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-13-502.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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