This National Institutes of Health (NIH) grant is offered to advance understanding of HIV-induced inflammation. Specifically, this funding opportunity encourages research focused on defining the molecular mechanisms by which HIV proteins and/or nucleic acids contribute to inflammation, immune activation, and persistent HIV presence even during effective viral suppression with Antiretroviral Therapy (ART). The primary purpose of this grant is to support studies that not only uncover these underlying mechanisms but also develop innovative therapeutic strategies. These new interventions aim to mitigate or entirely eliminate the detrimental effects of continued HIV expression in individuals on suppressive ART, thereby improving long-term health outcomes for those living with HIV.
Opportunity ID: 347120
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-23-018 |
| Funding Opportunity Title: | Defining Mechanisms of HIV Induced Inflammation and Immune Activation During Suppressive Antiretroviral Therapy (ART) (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 24, 2023 |
| Last Updated Date: | Mar 24, 2023 |
| Original Closing Date for Applications: | Aug 02, 2023 |
| Current Closing Date for Applications: | Aug 02, 2023 |
| Archive Date: | Sep 07, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Small businesses Native American tribal governments (Federally recognized) County governments Private institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages research focused on defining the molecular mechanisms by which HIV proteins and/or nucleic acids induce inflammation, immune activation and HIV persistence during viral suppression as well as on developing novel therapeutic strategies to mitigate or eliminate the effects of continued HIV expression. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-23-018.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 347120 Full Announcement-RFA-AI-23-018 -> RFA-AI-23-018-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00280802 | Jul 02, 2023 | Aug 02, 2023 | View |
Package 1
Mandatory forms
347120 RR_SF424_5_0-5.0.pdf
347120 PHS398_CoverPageSupplement_5_0-5.0.pdf
347120 RR_OtherProjectInfo_1_4-1.4.pdf
347120 PerformanceSite_4_0-4.0.pdf
347120 RR_KeyPersonExpanded_4_0-4.0.pdf
347120 PHS398_ResearchPlan_5_0-5.0.pdf
347120 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
347120 RR_Budget_3_0-3.0.pdf
347120 RR_SubawardBudget30_3_0-3.0.pdf
347120 PHS398_ModularBudget_1_2-1.2.pdf
347120 PHS_AssignmentRequestForm_3_0-3.0.pdf
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