This NIH Funding Opportunity Announcement offers a grant to significantly advance the understanding of the Druggable Genome. It specifically seeks proposals focused on adapting an ensemble of scalable technology platforms for the medium- to high-throughput characterization of functions for poorly understood or un-annotated proteins across four key classes. The primary objective is to move beyond conventional one-at-a-time research methods, establishing transformative technologies and streamlined experimental workflows. These platforms must incorporate multiple robust assay and physiological perturbation protocols to facilitate large-scale functional studies. This grant is for unveiling the functions of these uncharacterized proteins, contributing vital information to the Druggable Genome initiative by adopting innovative and efficient scientific approaches.
Opportunity ID: 242773
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-13-010 |
| Funding Opportunity Title: | Adaptation of Scalable Technologies to Illuminate the Druggable Genome (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 16, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 11, 2013 |
| Current Closing Date for Applications: | Dec 11, 2013 |
| Archive Date: | Jan 11, 2014 |
| Estimated Total Program Funding: | $2,500,000 |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The overarching goals of this Funding Opportunity Announcement (FOA) and the companion announcement (RFA-RM-13-011) are to foster the development of technologies and information management to facilitate the unveiling of the functions of the poorly characterized and/or un-annotated members in four protein classes of the Druggable Genome. This FOA calls for adaptation of an ensemble of scalable technology platforms to characterize functions of proteins as a large group at molecular and cellular levels in medium- to high-throughput fashion, rather than repeating the one at a time approach that might otherwise be undertaken. The objective is to establish transformative scalable technology platforms and streamlined experimental workflows incorporated with multiple robust assay and physiological perturbation protocols for large-scale functional studies of poorly characterized and/or un-annotated proteins encoded by the Druggable Genome. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.310 | FORMS-C | Forms-C | PKG00185290 | Nov 11, 2013 | Dec 11, 2013 | View |
Package 1
Mandatory forms
242773 RR_SF424_2_0-2.0.pdf
242773 PHS398_ResearchPlan_2_0-2.0.pdf
242773 PHS398_CoverPageSupplement_2_0-2.0.pdf
242773 RR_KeyPersonExpanded_2_0-2.0.pdf
242773 RR_OtherProjectInfo_1_3-1.3.pdf
242773 PerformanceSite_2_0-2.0.pdf
Optional forms
242773 RR_SubawardBudget30_1_3-1.3.pdf
242773 PlannedReport-1.0.pdf
242773 PHS398_CumulativeInclusionReport-1.0.pdf
242773 PHS398_ModularBudget_1_2-1.2.pdf
242773 RR_Budget_1_3-1.3.pdf
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