The National Institutes of Health (NIH) is offering this grant to identify and qualify extracellular RNA (exRNA)-based biomarkers derived from human body fluids like blood, saliva, and urine. This grant is for projects aiming to develop reliable, clinically relevant exRNA biomarkers to diagnose and monitor disease progression, and to assess therapy response. The primary purpose is to demonstrate tangible benefits for patients, impacting how they feel, function, and survive in clinical trials. Studies should focus on validating candidate exRNA-based biomarkers in well-defined patient populations and establishing new technologies or reliable assays for these validated markers.
Opportunity ID: 189277
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-12-013 |
| Funding Opportunity Title: | Clinical Utility of Extracellular RNA for Biomarker Development (UH2/UH3) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 03, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 13, 2012 |
| Current Closing Date for Applications: | Nov 13, 2012 |
| Archive Date: | Dec 14, 2012 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Special district governments Small businesses Public housing authorities/Indian housing authorities County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIH invites applications for projects that will identify and qualify extracellular RNA (exRNA)-based biomarkers derived from human body fluids, such as blood, saliva, urine, breast milk, amniotic fluid, cerebrospinal fluid, ascites and pleural effusions, in order to diagnose and monitor disease progression and response to therapy. The overall goal of this project is to develop reliable, well-defined and clinically relevant biomarkers derived from extracellular RNA that measure tangible benefits for patients in terms of how they feel, function, and survive in clinical trials. Appropriate studies under this FOA will identify and validate candidate exRNA-based biomarkers in well-defined patient populations, provide new technologies to monitor biomarkers or establish reliable assays for validated markers |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-013.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.310 | ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00136451 | Oct 12, 2012 | Nov 13, 2012 | View |
Package 1
Mandatory forms
189277 RR_SF424_1_2-1.2.pdf
189277 PerformanceSite_1_4-1.4.pdf
189277 RR_OtherProjectInfo_1_3-1.3.pdf
189277 RR_KeyPersonExpanded_1_2-1.2.pdf
189277 RR_Budget-1.1.pdf
189277 PHS398_CoverPageSupplement_1_4-1.4.pdf
189277 PHS398_ResearchPlan_1_3-1.3.pdf
189277 PHS398_Checklist_1_3-1.3.pdf
Optional forms
189277 RR_SubawardBudget30-1.2.pdf
189277 PHS_CoverLetter_1_2-1.2.pdf
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