This grant is for the purpose of funding early to late-stage clinical trials focused on developing and implementing pharmacological and non-pharmacological interventions to prevent and treat cognitive, behavioral, and neuropsychiatric changes associated with age-related cognitive decline, Alzheimer’s disease (AD), and Alzheimer’s disease-related dementias (ADRD). It also encourages studies to enhance trial design and methods, seeking to advance the understanding and treatment of these complex neurodegenerative conditions. The National Institutes of Health (NIH) offers this opportunity to accelerate research in this vital area, aiming to improve outcomes for individuals affected by these challenging conditions.
Opportunity ID: 355230
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-25-011 |
| Funding Opportunity Title: | Early- and Late-Stage Clinical Trials for the Spectrum of Alzheimer’s Disease/Alzheimer’s Disease-Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 01, 2024 |
| Last Updated Date: | Jul 01, 2024 |
| Original Closing Date for Applications: | Oct 17, 2024 |
| Current Closing Date for Applications: | Oct 17, 2024 |
| Archive Date: | Nov 22, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education State governments Special district governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities County governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to 1) invite applications that propose to develop and implement early to late stage clinical trials of promising pharmacological and non-pharmacological interventions to prevent and or treat the cognitive, behavioral,and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (ADRD) and 2) stimulate studies to enhance trial design and methods. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 355230 Full Announcement-RFA-AG-25-011 -> RFA-AG-25-011-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00287245 | Sep 17, 2024 | Oct 17, 2024 | View |
Package 1
Mandatory forms
355230 RR_SF424_5_0-5.0.pdf
355230 PHS398_CoverPageSupplement_5_0-5.0.pdf
355230 RR_OtherProjectInfo_1_4-1.4.pdf
355230 PerformanceSite_4_0-4.0.pdf
355230 RR_KeyPersonExpanded_4_0-4.0.pdf
355230 PHS398_ResearchPlan_5_0-5.0.pdf
355230 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
355230 RR_Budget_3_0-3.0.pdf
355230 RR_SubawardBudget30_3_0-3.0.pdf
355230 PHS398_ModularBudget_1_2-1.2.pdf
355230 PHS_AssignmentRequestForm_3_0-3.0.pdf
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