This National Institutes of Health (NIH) grant supports the development of innovative computational, bioinformatic, and statistical tools to understand the functional role of DNA variants linked to mental disorders. The primary goal is to determine the relevance of genetic variations identified through genome-wide association and sequencing studies. This initiative aims to advance methods for elucidating variant functionality, accounting for the unique complexities of brain diseases, ultimately informing the identification and validation of new targets for treatment development. This Collaborative R01 mechanism is designed for studies requiring two or more sites, where each site has its own Program Director/Principal Investigator, ensuring robust cross-site coordination, quality control, data management, and statistical analysis for comprehensive research outcomes.
Opportunity ID: 247577
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-13-391 |
| Funding Opportunity Title: | New Computational Methods for Understanding the Functional Role of DNA Variants that are Associated with Mental Disorders (Collaborative R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 13, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2017 |
| Current Closing Date for Applications: | Jan 07, 2017 |
| Archive Date: | Feb 07, 2017 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Special district governments Independent school districts City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) State governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support the development of advanced computational, bioinformatic and statistical tools to determine the functional relevance of genetic variants associated with mental disorders of complex etiologies identified through genome-wide association or sequencing studies. The overarching goal of this initiative is to support the development of innovative computational methods that facilitate the elucidation of the functionality of genetic variants associated with mental illness, taking into account the added complexities and nuances of brain diseases, and to ultimately inform the identification and validation of potential targets for novel treatment development. This FOA should be used when two or more sites are needed to complete the study. For a linked set of collaborative R01s, each site must have its own Program Director/Principal Investigator and the set of linked applications provide a mechanism for cross-site coordination, quality control, database management, statistical analysis, and reporting. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-13-391.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.242 | FORMS-C | Forms-C | PKG00189434 | Jan 05, 2014 | May 07, 2016 | View |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222246 | Apr 17, 2016 | Jan 07, 2017 | View |
Package 1
Mandatory forms
247577 RR_SF424_2_0-2.0.pdf
247577 PHS398_ResearchPlan_2_0-2.0.pdf
247577 PHS398_CoverPageSupplement_2_0-2.0.pdf
247577 RR_KeyPersonExpanded_2_0-2.0.pdf
247577 RR_OtherProjectInfo_1_3-1.3.pdf
247577 PerformanceSite_2_0-2.0.pdf
Optional forms
247577 RR_SubawardBudget30_1_3-1.3.pdf
247577 PlannedReport-1.0.pdf
247577 PHS398_CumulativeInclusionReport-1.0.pdf
247577 PHS398_ModularBudget_1_2-1.2.pdf
247577 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
247577 RR_SF424_2_0-2.0.pdf
247577 PHS398_CoverPageSupplement_3_0-3.0.pdf
247577 RR_OtherProjectInfo_1_3-1.3.pdf
247577 PerformanceSite_2_0-2.0.pdf
247577 RR_KeyPersonExpanded_2_0-2.0.pdf
247577 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
247577 RR_Budget_1_3-1.3.pdf
247577 RR_SubawardBudget30_1_3-1.3.pdf
247577 PHS398_ModularBudget_1_2-1.2.pdf
247577 PHS_Inclusion_Enrollment_Report-1.0.pdf
247577 PHS_AssignmentRequestForm-1.0.pdf