This grant, supported by the National Institutes of Health, seeks to establish vital resource networks dedicated to misfolded protein polymorphisms within Alzheimer’s disease (AD) and its related dementias (ADRD). The core purpose is to standardize the production and facilitate the widespread distribution of crucial protein components, including seeds, oligomers, and fibrils, to the broader research community. This effort is designed to significantly clarify and improve the reproducibility of experiments conducted in the AD/ADRD field. Long-term objectives encompass the development of comprehensive standards for these proteins, an enhanced understanding of their pathological contributions, and the application of newly developed analytical tools to directly correlate patient-to-patient variations in A?, ?-synuclein, and tau polymorphs.
Opportunity ID: 336746
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-22-030 |
| Funding Opportunity Title: | Resource Networks for Protein Polymorphisms in Alzheimers Disease and its Related Dementias (AD/ADRD) (U24 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 29, 2021 |
| Last Updated Date: | Nov 29, 2021 |
| Original Closing Date for Applications: | Jan 10, 2022 |
| Current Closing Date for Applications: | Jan 10, 2022 |
| Archive Date: | Feb 15, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Small businesses Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Native American tribal organizations (other than Federally recognized tribal governments) State governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites U24 Cooperative Agreement applications aiming to establish misfolded protein polymorphisms resource networks in the area of Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (ADRD). The central goal of these resource networks is to standardize and distribute seed, oligomers, and fibrils to other investigators in order to clarify and improve the reproducibility of experiments in AD/ADRD. Establishing standards, understanding the pathological roles of these protein polymorphs, and using newly developed analytic tools to address the direct correlation between patient-to-patient variations in A, ?-synuclein, and tau polymorphs are the long-term goals of the resource networks supported by this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-22-030.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270658 | Dec 10, 2021 | Jan 10, 2022 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00270657 | Dec 10, 2021 | Jan 10, 2022 | View |
Package 1
Mandatory forms
336746 RR_SF424_5_0-5.0.pdf
336746 PHS398_CoverPageSupplement_5_0-5.0.pdf
336746 RR_OtherProjectInfo_1_4-1.4.pdf
336746 PerformanceSite_4_0-4.0.pdf
336746 RR_KeyPersonExpanded_4_0-4.0.pdf
336746 RR_Budget_3_0-3.0.pdf
336746 PHS398_ResearchPlan_4_0-4.0.pdf
336746 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
336746 RR_SubawardBudget30_3_0-3.0.pdf
336746 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
336746 RR_SF424_2_0-2.0.pdf
336746 PHS398_CoverPageSupplement_5_0-5.0.pdf
336746 RR_OtherProjectInfo_1_4-1.4.pdf
336746 PerformanceSite_2_0-2.0.pdf
336746 RR_KeyPersonExpanded_2_0-2.0.pdf
336746 RR_Budget_1_4-1.4.pdf
336746 PHS398_ResearchPlan_4_0-4.0.pdf
336746 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
336746 RR_SubawardBudget30_1_4-1.4.pdf
336746 PHS_AssignmentRequestForm_3_0-3.0.pdf
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