The National Institutes of Health (NIH) is offering this grant to investigate the profound effects of addictive substances on the developmental trajectories of molecularly-defined CNS cells and circuits. This grant is for the purpose of supporting projects that carry out systematic and highly granular quantitative characterizations. Emphasis is placed on understanding the impact of in utero and/or postnatal substance exposure on the numbers, spatial distribution, and connectivity of specific cell types, across whole brains or within clinically relevant distributed circuits. The ultimate goals are to identify critical developmental windows and the cellular mechanisms mediating the protracted developmental impact of addictive substances. This research will ultimately inform clinical practice by complementing data from human longitudinal neuroimaging studies.
Opportunity ID: 344404
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-23-036 |
| Funding Opportunity Title: | Investigating the Effects of Addictive Substances on Brain Developmental Trajectories Using Innovative Scalable Methods for Quantification of Cell Identity, Lineage and Connectivity (R01 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 08, 2022 |
| Last Updated Date: | Nov 08, 2022 |
| Original Closing Date for Applications: | Feb 02, 2023 |
| Current Closing Date for Applications: | Feb 02, 2023 |
| Archive Date: | Mar 10, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments State governments Small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) will support projects that investigate the effects of addictive substances on developmental trajectories of molecularly-defined CNS cells and circuits. Emphasis is on carrying out systematic and highly granular quantitative characterizations of the impact of in utero and/or postnatal substance exposure on the numbers, spatial distribution and connectivity of molecularly-defined cells, across whole brains or within distributed circuits of clinical relevance. The ultimate goals of the program are to identify critical developmental windows and cellular mechanisms mediating the protracted developmental impact of addictive substances, and will inform clinical practice, by complementing the data from human longitudinal neuroimaging studies such as the ABCD study.? |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-23-036.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 344404 Full Announcement-RFA-DA-23-036 -> RFA-DA-23-036-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278189 | Jan 02, 2023 | Feb 02, 2023 | View |
Package 1
Mandatory forms
344404 RR_SF424_5_0-5.0.pdf
344404 PHS398_CoverPageSupplement_5_0-5.0.pdf
344404 RR_OtherProjectInfo_1_4-1.4.pdf
344404 PerformanceSite_4_0-4.0.pdf
344404 RR_KeyPersonExpanded_4_0-4.0.pdf
344404 PHS398_ResearchPlan_5_0-5.0.pdf
344404 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
344404 RR_Budget_3_0-3.0.pdf
344404 RR_SubawardBudget30_3_0-3.0.pdf
344404 PHS398_ModularBudget_1_2-1.2.pdf
344404 PHS_AssignmentRequestForm_3_0-3.0.pdf
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