The National Institutes of Health (NIH) is offering this grant to support mechanism-focused research aimed at promoting adherence to healthful behaviors. This grant is for the purpose of identifying psychological and interpersonal mechanisms that drive adherence to lifestyle changes essential for preventing cognitive decline, Mild Cognitive Impairment (MCI), and Alzheimer’s disease (AD) and AD-related dementias (ADRD). Applicants will study these mechanisms within behavior change trials, seeking to discover malleable targets that, when modified, can strengthen sustained engagement in behaviors beneficial for cognitive health and AD/ADRD prevention. Utilizing the R61/R33 phased award, the R61 phase will fund pilot research to identify and assess adherence targets, transitioning to the R33 phase for rigorous intervention studies based on R61 findings. Transition is contingent on meeting specific R61 go/no-go criteria.
Opportunity ID: 343910
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-23-034 |
| Funding Opportunity Title: | Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 03, 2022 |
| Last Updated Date: | Oct 03, 2022 |
| Original Closing Date for Applications: | Jan 20, 2023 |
| Current Closing Date for Applications: | Jan 20, 2023 |
| Archive Date: | Feb 25, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Native American tribal governments (Federally recognized) County governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications to address psychological and interpersonal mechanisms driving adherence to behaviors or lifestyle changes relevant to prevention of cognitive decline, Mild Cognitive Impairment (MCI), and Alzheimer’s disease (AD) and AD-related dementias (ADRD). Mechanisms of adherence may be studied in new, early- to late-stage (including Stage I-IV) behavior change trials. Applications will seek to identify malleable, mechanistic, psychological, or interpersonal targets that, if modified, will strengthen adherence to, maintenance of, and continued/renewed engagement in behaviors that may promote cognitive health and prevent AD/ADRD. This FOA utilizes the R61/R33 Exploratory/Developmental Phased Award activity code. The R61 phase will support pilot research to identify, measure, and assess the malleability of psychological or interpersonal adherence-relevant targets that, if successful, can transition to the R33 phase. The R33 phase will utilize results from the R61 phase to implement rigorous, proof-of-concept intervention studies. The transition from the R61 to the R33 phase will be administratively reviewed for, and be dependent upon, successful completion of the go/no-go criteria specified for the R61 phase. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-23-034.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343910 Full Announcement-RFA-AG-23-034 -> RFA-AG-23-034-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00277130 | Dec 20, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278378 | Dec 20, 2022 | Jan 20, 2023 | View |
Package 1
Mandatory forms
343910 RR_SF424_5_0-5.0.pdf
343910 PHS398_CoverPageSupplement_5_0-5.0.pdf
343910 RR_OtherProjectInfo_1_4-1.4.pdf
343910 PerformanceSite_4_0-4.0.pdf
343910 RR_KeyPersonExpanded_4_0-4.0.pdf
343910 RR_Budget_3_0-3.0.pdf
343910 PHS398_ResearchPlan_4_0-4.0.pdf
343910 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343910 RR_SubawardBudget30_3_0-3.0.pdf
343910 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343910 RR_SF424_5_0-5.0.pdf
343910 PHS398_CoverPageSupplement_5_0-5.0.pdf
343910 RR_OtherProjectInfo_1_4-1.4.pdf
343910 PerformanceSite_4_0-4.0.pdf
343910 RR_KeyPersonExpanded_4_0-4.0.pdf
343910 RR_Budget_3_0-3.0.pdf
343910 PHS398_ResearchPlan_5_0-5.0.pdf
343910 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343910 RR_SubawardBudget30_3_0-3.0.pdf
343910 PHS_AssignmentRequestForm_3_0-3.0.pdf
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