This Notice of Funding Opportunity from the National Institutes of Health (NIH) is offering this grant to support the development of clinical research platforms. This initiative is designed to enable future clinical trials that will determine the effectiveness of combining HIV cure strategies when optimally tailored to individual participants. The ultimate goal is for the results from these proof-of-concept studies to inform and prioritize the development of more broad-based curative strategies, aiming for efficacy in all people living with HIV. This grant will support multidisciplinary teams to conduct coordinated basic and pre-clinical research, profiling participants’ intact, rebound-competent HIV reservoirs and their immunologic backgrounds. This information will then be used to develop and test tailored combinations of HIV curative approaches.
Opportunity ID: 353103
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-24-011 |
| Funding Opportunity Title: | Tailoring HIV Curative Strategies to the Participant (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 21, 2024 |
| Last Updated Date: | Mar 21, 2024 |
| Original Closing Date for Applications: | Jul 30, 2024 |
| Current Closing Date for Applications: | Jul 30, 2024 |
| Archive Date: | Sep 04, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $2,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education County governments Independent school districts For profit organizations other than small businesses City or township governments Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to support the development of clinical research platforms that will enable future clinical trials to determine whether combinations of HIV cure strategies can be effective when optimally tailored to the participants. The ultimate goal is for the results of such proof-of-concept clinical studies to inform the development and prioritization of more broad-based curative strategies that will be effective in all people living with HIV. This NOFO will support multidisciplinary teams to conduct coordinated basic and pre-clinical research to profile participants intact, rebound-competent HIV reservoirs and immunologic backgrounds and use that information to develop and test combinations of HIV curative approaches that are specifically tailored to those participants. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 353103 Full Announcement-RFA-AI-24-011 -> RFA-AI-24-011-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285479 | Jun 30, 2024 | Jul 30, 2024 | View |
Package 1
Mandatory forms
353103 RR_SF424_5_0-5.0.pdf
353103 PHS398_CoverPageSupplement_5_0-5.0.pdf
353103 RR_OtherProjectInfo_1_4-1.4.pdf
353103 PerformanceSite_4_0-4.0.pdf
353103 RR_KeyPersonExpanded_4_0-4.0.pdf
353103 RR_Budget_3_0-3.0.pdf
353103 PHS398_ResearchPlan_5_0-5.0.pdf
353103 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353103 RR_SubawardBudget30_3_0-3.0.pdf
353103 PHS_AssignmentRequestForm_3_0-3.0.pdf
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