The National Institutes of Health (NIH) is offering this grant to support pilot projects investigating understudied proteins associated with rare diseases. This grant is for the purpose of generating preliminary data and/or developing tools around eligible understudied proteins. The NOFO specifically targets members of druggable protein families with known links to rare diseases. The aim is to jumpstart research, providing funding for basic biochemical and/or biological work. Projects should further the characterization of these proteins within the context of rare disease, laying groundwork for future advancements in understanding and potentially treating these conditions.
Opportunity ID: 356879
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-122 |
| Funding Opportunity Title: | Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 28, 2024 |
| Last Updated Date: | Oct 28, 2024 |
| Original Closing Date for Applications: | Nov 16, 2027 |
| Current Closing Date for Applications: | Nov 16, 2027 |
| Archive Date: | Dec 22, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $100,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to elucidate a role for understudied proteins in rare disease. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s). A list of eligible proteins is provided and are members of druggable protein families that have a known association with a rare disease. This NOFO is intended to jumpstart research on understudied proteins that are associated with rare diseases and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins within the context of rare disease. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-122.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356879 Full Announcement-PAR-25-122 -> PAR-25-122-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288432 | Jan 16, 2025 | Nov 16, 2027 | View |
Package 1
Mandatory forms
356879 RR_SF424_5_0-5.0.pdf
356879 PHS398_CoverPageSupplement_5_0-5.0.pdf
356879 RR_OtherProjectInfo_1_4-1.4.pdf
356879 PerformanceSite_4_0-4.0.pdf
356879 RR_KeyPersonExpanded_4_0-4.0.pdf
356879 PHS398_ResearchPlan_5_0-5.0.pdf
356879 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356879 RR_Budget_3_0-3.0.pdf
356879 RR_SubawardBudget30_3_0-3.0.pdf
356879 PHS398_ModularBudget_1_2-1.2.pdf
356879 PHS_AssignmentRequestForm_4_0-4.0.pdf
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