The National Institutes of Health is offering a grant to study the mechanisms of generating novel peptidic and non-peptidic ligands presented by MHC class I and II molecules, and their impact on immune responses, pathogenesis, and immune-mediated diseases. Research may lead to the development of tools for immune-based therapeutics and vaccines. Closing date for applications is January 7, 2022.
Opportunity ID: 310316
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-19-067 |
| Funding Opportunity Title: | Processing and Presentation of Non-Conventional MHC Ligands (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 13, 2018 |
| Last Updated Date: | Nov 13, 2018 |
| Original Closing Date for Applications: | Jan 07, 2022 |
| Current Closing Date for Applications: | Jan 07, 2022 |
| Archive Date: | Feb 12, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) City or township governments County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Special district governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications to characterize antigen processing and presentation mechanisms used in the generation of novel peptidic and non-peptidic ligands presented by classical and non-classical MHC class I and class II molecules, and to determine the contribution of these unique antigenic ligands to: protective immune responses to infectious pathogens and/or vaccines; pathogen-associated immune pathogenesis; and/or in the induction/progression or prevention of immune-mediated diseases. These studies may facilitate the development of novel tools and reagents to advance design of immune-based therapeutics and vaccines. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-19-067.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00246219 | Jan 05, 2019 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00259212 | Jan 05, 2019 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269672 | Oct 28, 2021 | Jan 07, 2022 | View |
Package 1
Mandatory forms
310316 RR_SF424_2_0-2.0.pdf
310316 PHS398_CoverPageSupplement_4_0-4.0.pdf
310316 RR_OtherProjectInfo_1_4-1.4.pdf
310316 PerformanceSite_2_0-2.0.pdf
310316 RR_KeyPersonExpanded_2_0-2.0.pdf
310316 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
310316 RR_Budget_1_4-1.4.pdf
310316 RR_SubawardBudget30_1_4-1.4.pdf
310316 PHS398_ModularBudget_1_2-1.2.pdf
310316 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
310316 RR_SF424_2_0-2.0.pdf
310316 PHS398_CoverPageSupplement_5_0-5.0.pdf
310316 RR_OtherProjectInfo_1_4-1.4.pdf
310316 PerformanceSite_2_0-2.0.pdf
310316 RR_KeyPersonExpanded_2_0-2.0.pdf
310316 PHS398_ResearchPlan_4_0-4.0.pdf
310316 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
310316 RR_Budget_1_4-1.4.pdf
310316 RR_SubawardBudget30_1_4-1.4.pdf
310316 PHS398_ModularBudget_1_2-1.2.pdf
310316 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
310316 RR_SF424_5_0-5.0.pdf
310316 PHS398_CoverPageSupplement_5_0-5.0.pdf
310316 RR_OtherProjectInfo_1_4-1.4.pdf
310316 PerformanceSite_4_0-4.0.pdf
310316 RR_KeyPersonExpanded_4_0-4.0.pdf
310316 PHS398_ResearchPlan_4_0-4.0.pdf
310316 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
310316 RR_Budget_3_0-3.0.pdf
310316 RR_SubawardBudget30_3_0-3.0.pdf
310316 PHS398_ModularBudget_1_2-1.2.pdf
310316 PHS_AssignmentRequestForm_3_0-3.0.pdf
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