The NIH is offering this grant to fund projects aimed at determining the principles guiding the selection and function of extracellular RNA (exRNA) molecules. This grant is for research focusing on key aspects including exRNA biogenesis, biodistribution, uptake by target cells, and the physiological impact of delivered exRNAs. Successful applications are expected to involve multidisciplinary teams, utilizing innovative tools, technologies, and analytical approaches to achieve research goals. The primary purpose is to advance the understanding of exRNA communication in both health and disease states, contributing to new insights into biological processes and potential therapeutic targets.
Opportunity ID: 189273
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-12-012 |
| Funding Opportunity Title: | Extracellular RNA Biogenesis, Biodistribution, Uptake, and Effector Function (U19) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 03, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 13, 2012 |
| Current Closing Date for Applications: | Nov 13, 2012 |
| Archive Date: | Dec 14, 2012 |
| Estimated Total Program Funding: | $7,200,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts County governments Private institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities City or township governments Public and State controlled institutions of higher education Small businesses Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIH invites applications for projects to determine the principles that guide the selection of regulatory RNA molecules for extracellular transport and to determine the function of these extracellular RNAs (exRNAs). The main scientific areas of interest include (1) exRNA biogenesis, (2) exRNA biodistribution, (3) uptake of exRNA by target cells, and (4) the physiological impact of delivered exRNA in target cells and tissues. Enabling tools, technologies, bioreagents, and innovative analytical approaches will likely be required to achieve the research goals. Therefore, awards funded under this FOA are anticipated to involve research conducted by multidisciplinary teams of investigators and focus on the role of exRNA communication in health and disease. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-012.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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