This NIH grant supports large-scale pragmatic trials and implementation science studies to enhance pain management and decrease opioid medication usage. The grant involves a phased approach, with initial funding for a planning phase that may transition to an implementation phase. The objective is to discover effective strategies for enhancing pain management and diminishing the reliance on opioids within healthcare systems. Applicants must propose interventions embedded in real-world healthcare settings, with trials carried out across multiple healthcare systems. Collaboration with the NIH HCS Research Collaboratory and the Collaboratory Coordinating Center is required for successful execution of the research. Application deadline is on February 8, 2019.
Opportunity ID: 310979
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AT-19-004 |
| Funding Opportunity Title: | HEAL Initiative: Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) (UG3/UH3, Clinical Trials Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 10, 2018 |
| Last Updated Date: | Dec 10, 2018 |
| Original Closing Date for Applications: | Feb 08, 2019 |
| Current Closing Date for Applications: | Feb 08, 2019 |
| Archive Date: | Mar 16, 2019 |
| Estimated Total Program Funding: | $4,500,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education Independent school districts For profit organizations other than small businesses County governments Native American tribal governments (Federally recognized) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages UG3/UH3 phased cooperative research applications to conduct efficient, large-scale pragmatic trial or implementation science study designs to improve pain management and reduce the use of opioid medications. Awards made under this FOA will initially support a one-year milestone-driven planning phase (UG3), with possible transition to an implementation phase (UH3). UG3 projects that have met the scientific milestone and feasibility requirements may transition to the UH3 phase. The UG3/UH3 application must be submitted as a single application, following the instructions described in this FOA. The overall goal of this initiative is to identify effective methods to improve the management of pain and reduce the need for opioid medications at the health care system level. This FOA requires that the intervention under study be embedded into health care delivery system, real world settings. Studies can propose to integrate interventions that have demonstrated efficacy into health care system; or implement health care system changes to improve adherence to evidence-based guidelines. Trials must be conducted across two or more health care systems (HCS) and must be conducted as part of the NIH HCS Research Collaboratory supported through the NIH Common Fund. (See https://commonfund.nih.gov/hcscollaboratory). The NIH HCS Research Collaboratory Program has established a Collaboratory Coordinating Center (CCC) that is providing national leadership and technical expertise in all aspects of research with HCS. After awards are made by NIH, the CCC (http://rethinkingclinicaltrials.org/about-nih-collaboratory/) and the NIH will work with successful awardees from this FOA to facilitate the planning and rapid execution of high impact trials that conduct research studies in partnerships with health care delivery systems. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-19-004.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00246782 | Jan 08, 2019 | Feb 08, 2019 | View |
Package 1
Mandatory forms
310979 RR_SF424_2_0-2.0.pdf
310979 PHS398_CoverPageSupplement_4_0-4.0.pdf
310979 RR_OtherProjectInfo_1_4-1.4.pdf
310979 PerformanceSite_2_0-2.0.pdf
310979 RR_KeyPersonExpanded_2_0-2.0.pdf
310979 RR_Budget_1_4-1.4.pdf
310979 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
310979 RR_SubawardBudget30_1_4-1.4.pdf
310979 PHS_AssignmentRequestForm_2_0-2.0.pdf
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