This grant is for supporting research aimed at identifying novel druggable targets and discovering optimizable probes. The ultimate goal is to develop safe and effective medications to prevent and treat opioid use disorders (OUDs), opioid overdose, and co-occurring opioid-polysubstance use. This funding opportunity is a key component of the NIH Helping to End Addictions Long-term (HEAL) initiative. The HEAL initiative seeks to accelerate the creation of innovative medications addressing the full spectrum of the opioid addiction cycle, including the transition to chronic use, managing withdrawal symptoms, reducing cravings, preventing relapse, and mitigating overdose risks. This comprehensive approach is crucial for combating the opioid crisis.
Opportunity ID: 349404
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-24-064 |
| Funding Opportunity Title: | HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.213 — Research and Training in Complementary and Integrative Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 19, 2023 |
| Last Updated Date: | Jul 19, 2023 |
| Original Closing Date for Applications: | Feb 01, 2024 |
| Current Closing Date for Applications: | Feb 01, 2024 |
| Archive Date: | Mar 08, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Special district governments Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to support research focusing on the identification of druggable new targets and discovery of optimizable probes for development of safe and efficacious medications to prevent and treat opioid use disorders (OUDs), opioid overdose, and opioid-polysubstance use comorbidities. This notice of funding opportunity is part of the NIH Helping to End Addictions Long-term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-064.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 349404 Full Announcement-RFA-DA-24-064 -> RFA-DA-24-064-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282604 | Jan 01, 2024 | Feb 01, 2024 | View |
Package 1
Mandatory forms
349404 RR_SF424_5_0-5.0.pdf
349404 PHS398_CoverPageSupplement_5_0-5.0.pdf
349404 RR_OtherProjectInfo_1_4-1.4.pdf
349404 PerformanceSite_4_0-4.0.pdf
349404 RR_KeyPersonExpanded_4_0-4.0.pdf
349404 PHS398_ResearchPlan_5_0-5.0.pdf
349404 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349404 RR_Budget_3_0-3.0.pdf
349404 RR_SubawardBudget30_3_0-3.0.pdf
349404 PHS398_ModularBudget_1_2-1.2.pdf
349404 PHS_AssignmentRequestForm_3_0-3.0.pdf
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