This grant, offered by participating NIH Institutes and Centers, aims to stimulate research in developing assays for high-throughput screening (HTS) to advance Probe and Pre-therapeutic Discovery. The primary purpose is two-fold: first, to create assays targeting specific biological mechanisms and diseases, facilitating the discovery of small molecule compounds as potential probes or pre-therapeutic leads. Second, it encourages collaborations with expert screening centers to effectively implement these HTS assays for chemical probe development. A key criterion for this initiative is novelty, emphasizing avoidance of extensively targeted areas. Successful assays will establish a stream of high-quality screening tools for the NIH Molecular Libraries Program and other academic centers, and must align with at least one participating NIH Institute’s research mission.
Opportunity ID: 243833
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-13-364 |
| Funding Opportunity Title: | Development of Assays for High-Throughput Screening for Use in Probe and Pre-therapeutic Discovery (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 27, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2017 |
| Current Closing Date for Applications: | Jan 07, 2017 |
| Archive Date: | Feb 07, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Native American tribal governments (Federally recognized) Small businesses Public housing authorities/Indian housing authorities State governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The participating NIH Institutes and Centers invite Research Project Grant (R01) applications to develop assays for high throughput screening (HTS) for use in Probe and Pre-therapeutic Discovery. Through this FOA, NIH wishes to stimulate research in 1) developing assays for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; and 2) establishing collaboration with screening centers that have the requisite expertise and experience needed in implementation of HTS assays for the discovery and development of small molecule chemical probes. This FOA seeks to establish a stream of scientifically and technologically outstanding assays for screening by the NIH Molecular Libraries Production Centers Network (MLPCN) in the Molecular Libraries Program (MLP) and other academic centers. One important criterion for this initiative is novelty, so applicants are therefore encouraged to avoid focusing on areas and approaches that have been extensively targeted in other settings. Assays should be relevant to the scope of research in at least one of the participating NIH Institutes. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-13-364.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | Forms-C | PKG00186250 | Jan 05, 2014 | May 07, 2016 | View | |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222111 | Apr 17, 2016 | Jan 07, 2017 | View |
Package 1
Mandatory forms
243833 RR_SF424_2_0-2.0.pdf
243833 PHS398_ResearchPlan_2_0-2.0.pdf
243833 PHS398_CoverPageSupplement_2_0-2.0.pdf
243833 RR_KeyPersonExpanded_2_0-2.0.pdf
243833 RR_OtherProjectInfo_1_3-1.3.pdf
243833 PerformanceSite_2_0-2.0.pdf
Optional forms
243833 RR_SubawardBudget30_1_3-1.3.pdf
243833 PlannedReport-1.0.pdf
243833 PHS398_CumulativeInclusionReport-1.0.pdf
243833 PHS398_ModularBudget_1_2-1.2.pdf
243833 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
243833 RR_SF424_2_0-2.0.pdf
243833 PHS398_CoverPageSupplement_3_0-3.0.pdf
243833 RR_OtherProjectInfo_1_3-1.3.pdf
243833 PerformanceSite_2_0-2.0.pdf
243833 RR_KeyPersonExpanded_2_0-2.0.pdf
243833 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
243833 RR_Budget_1_3-1.3.pdf
243833 RR_SubawardBudget30_1_3-1.3.pdf
243833 PHS398_ModularBudget_1_2-1.2.pdf
243833 PHS_Inclusion_Enrollment_Report-1.0.pdf
243833 PHS_AssignmentRequestForm-1.0.pdf
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