This grant is for exploring the biological mechanisms through which environmental exposures influence brain and behavioral functioning, increasing risk for psychiatric disorders with onset in late-childhood, adolescence, or early adulthood. The R21 mechanism supports high-risk, novel, exploratory, and developmental research projects. Priority is given to investigations that advance understanding of psychiatric conditions with less established environmental links. The FOA encourages a range of mechanistic approaches, from in vitro systems to whole organism models, to examine the link between environmental chemicals and psychiatric pathogenesis. Research into the joint contribution of genes and environment is also welcomed. Knowledge gained will inform the development of improved intervention, prevention, and therapeutic strategies.
Opportunity ID: 343906
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-22-009 |
| Funding Opportunity Title: | Biological Basis for how Environmental Exposures Impact Risk for Psychiatric Disorders (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 03, 2022 |
| Last Updated Date: | Oct 03, 2022 |
| Original Closing Date for Applications: | Feb 22, 2023 |
| Current Closing Date for Applications: | Feb 22, 2023 |
| Archive Date: | Mar 30, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Small businesses For profit organizations other than small businesses Independent school districts Private institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities State governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The objective of this funding opportunity announcement (FOA) is to solicit applications that propose to better understand the biological basis by which environmental exposures alter brain and behavioral functioning to increase risk for psychiatric disorders with onset in late-childhood, adolescence, or early adulthood. The R21 grant mechanism is intended to encourage exploratory and developmental research projects that are high-risk and/or use novel approaches with potential for significant impact. Investigations that further advance our understanding of psychiatric conditions where there is less evidence of an environmental exposure link are of particular interest. Since basic and pre-clinical research is critical for the study of neurobiological mechanisms that drive complex behaviors including mental illness, the focus of this FOA is to encourage a range of mechanistic approaches, from in vitro systems to whole organism models, to examine the link between environmental chemicals and possible contribution to the pathogenesis of psychiatric abnormalities. Investigations that further advance our understanding of the joint contribution of genes and environment in the risk for psychiatric disorders are also welcomed. It is anticipated that knowledge gained from the research supported by this FOA will inform the development of improved intervention, prevention and/or therapeutic strategies. This FOA will use the NIH Exploratory/Developmental Research Grant (R21) award mechanism and runs in parallel with another FOA, RFA-ES-22-008, which encourages applications under the R01 mechanism. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-22-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343906 Full Announcement-RFA-ES-22-009 -> RFA-ES-22-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00277126 | Jan 22, 2023 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278170 | Jan 22, 2023 | Feb 22, 2023 | View |
Package 1
Mandatory forms
343906 RR_SF424_5_0-5.0.pdf
343906 PHS398_CoverPageSupplement_5_0-5.0.pdf
343906 RR_OtherProjectInfo_1_4-1.4.pdf
343906 PerformanceSite_4_0-4.0.pdf
343906 RR_KeyPersonExpanded_4_0-4.0.pdf
343906 PHS398_ResearchPlan_4_0-4.0.pdf
343906 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343906 RR_Budget_3_0-3.0.pdf
343906 RR_SubawardBudget30_3_0-3.0.pdf
343906 PHS398_ModularBudget_1_2-1.2.pdf
343906 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343906 RR_SF424_5_0-5.0.pdf
343906 PHS398_CoverPageSupplement_5_0-5.0.pdf
343906 RR_OtherProjectInfo_1_4-1.4.pdf
343906 PerformanceSite_4_0-4.0.pdf
343906 RR_KeyPersonExpanded_4_0-4.0.pdf
343906 PHS398_ResearchPlan_5_0-5.0.pdf
343906 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343906 RR_Budget_3_0-3.0.pdf
343906 RR_SubawardBudget30_3_0-3.0.pdf
343906 PHS398_ModularBudget_1_2-1.2.pdf
343906 PHS_AssignmentRequestForm_3_0-3.0.pdf
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