This grant, offered by NIH, is for the purpose of soliciting innovative analytics and technologies aimed at identifying and mapping senescent cells within murine tissues with high resolution. The program supports the rapid development and demonstration of feasible tools that can be integrated and scaled for broad application. The initial two-year UG3 phase focuses on proving the concept and feasibility of these emerging technologies. Successful projects will then transition to the UH3 phase, which involves further validation, optimization, and scaling up the technology. Ultimately, the UH3 phase aims to generate production-level data and apply the developed technology to describe cellular senescence across a mouse’s life course, such as during development or lifespan studies. Applicants must submit proposals for both UG3 and UH3 phases concurrently.
Opportunity ID: 336320
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-22-005 |
| Funding Opportunity Title: | Cellular Senescence Network: Technology Development and Application in Murine Systems (UG3/UH3 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 28, 2021 |
| Last Updated Date: | Oct 28, 2021 |
| Original Closing Date for Applications: | Jan 19, 2022 |
| Current Closing Date for Applications: | Jan 19, 2022 |
| Archive Date: | Feb 24, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Small businesses Special district governments County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this FOA is to solicit novel analytics and technologies to identify and map senescent cells in murine tissues at high resolution. This FOA supports the accelerated proof-of-principle demonstration of promising tools, techniques and methods that can be integrated, scaled, and applied to multiple murine tissues. The initial two-year UG3 phase will support the development and demonstration of feasibility of these emerging technologies in the identification and mapping of senescent cells in murine tissues. The subsequent UH3 phase is to support initial validation in multiple optimization and scale-up, generation of production level data and the application of the technology to describe cellular senescence in a mouse life course situation (for example development or lifespan). Investigators responding to this FOA must submit both UG3 and UH3 projects as part of a single application. UG3 projects that have met their quantifiable milestones will be administratively considered by NIH staff and prioritized for transition to the UH3 phase, depending on the availability of funds. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-22-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00269656 | Dec 20, 2021 | Jan 19, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270478 | Dec 20, 2021 | Jan 19, 2022 | View |
Package 1
Mandatory forms
336320 RR_SF424_2_0-2.0.pdf
336320 PHS398_CoverPageSupplement_5_0-5.0.pdf
336320 RR_OtherProjectInfo_1_4-1.4.pdf
336320 PerformanceSite_2_0-2.0.pdf
336320 RR_KeyPersonExpanded_2_0-2.0.pdf
336320 RR_Budget_1_4-1.4.pdf
336320 PHS398_ResearchPlan_4_0-4.0.pdf
336320 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
336320 RR_SubawardBudget30_1_4-1.4.pdf
336320 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
336320 RR_SF424_5_0-5.0.pdf
336320 PHS398_CoverPageSupplement_5_0-5.0.pdf
336320 RR_OtherProjectInfo_1_4-1.4.pdf
336320 PerformanceSite_4_0-4.0.pdf
336320 RR_KeyPersonExpanded_4_0-4.0.pdf
336320 RR_Budget_3_0-3.0.pdf
336320 PHS398_ResearchPlan_4_0-4.0.pdf
336320 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
336320 RR_SubawardBudget30_3_0-3.0.pdf
336320 PHS_AssignmentRequestForm_3_0-3.0.pdf
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