This grant is for the purpose of advancing research into Substance Use Disorders (SUDs) by supporting innovative high-throughput screening and similar transformative methodologies. The primary goal is to identify novel receptors, signal transducers, or small molecules capable of modulating critical SUD-relevant signal transduction pathways, including dopamine, opioid, cannabinoid, and nicotinic pathways, or other appropriately justified pathways. Projects funded through this initiative are also encouraged to incorporate secondary screens and robust validation processes for identified key hits, ensuring the robustness and translational potential of the discoveries. This opportunity aims to accelerate the discovery of new therapeutic targets and interventions for opioid and other substance use disorders.
Opportunity ID: 331326
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-22-006 |
| Funding Opportunity Title: | High-throughput Discovery and Validation of Novel Signal Transducers or Small Molecules that Modulate Opioid or other Substance Use Disorder Relevant Pathways (R01 – Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 04, 2021 |
| Last Updated Date: | Feb 04, 2021 |
| Original Closing Date for Applications: | Sep 15, 2021 |
| Current Closing Date for Applications: | Sep 15, 2021 |
| Archive Date: | Oct 21, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education Native American tribal governments (Federally recognized) County governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments For profit organizations other than small businesses Small businesses City or township governments Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA will support high-throughput screening or similar transformative approaches to identify novel receptors, signal transducers, or small molecules that modulate SUD-relevant signal transduction pathways (dopamine, opioid, cannabinoid, nicotinic, or other appropriately justified pathway). These projects may also include secondary screens and/or validation of key hits identified. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-006.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00265296 | Aug 15, 2021 | Sep 15, 2021 | View |
Package 1
Mandatory forms
331326 RR_SF424_2_0-2.0.pdf
331326 PHS398_CoverPageSupplement_5_0-5.0.pdf
331326 RR_OtherProjectInfo_1_4-1.4.pdf
331326 PerformanceSite_2_0-2.0.pdf
331326 RR_KeyPersonExpanded_2_0-2.0.pdf
331326 PHS398_ResearchPlan_4_0-4.0.pdf
331326 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
331326 RR_Budget_1_4-1.4.pdf
331326 RR_SubawardBudget30_1_4-1.4.pdf
331326 PHS398_ModularBudget_1_2-1.2.pdf
331326 PHS_AssignmentRequestForm_3_0-3.0.pdf
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