The National Institutes of Health is offering the NIH Microphysiological Systems Data Center U24 Grant for the Tissue Chip Testing Center (TCTC) to support the NIH Tissue Chip Consortium. This grant aims to establish a central data center for the management, mining, and sharing of tissue chip (TC) data across various organs, diseases, and platforms. The center will provide public and tiered access to TC information for researchers, physicians, pharmaceutical industry, and government agencies. The focus is on developing a coordinated data management system for diverse data types used in drug screening and testing, in collaboration with the IQ Consortium members.
Opportunity ID: 299571
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TR-18-005 |
| Funding Opportunity Title: | Microphysiological Systems Data Center U24 (Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.350 — National Center for Advancing Translational Sciences |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 20, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 21, 2018 |
| Current Closing Date for Applications: | Mar 21, 2018 |
| Archive Date: | Apr 26, 2018 |
| Estimated Total Program Funding: | $1,100,000 |
| Award Ceiling: | $700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Native American tribal governments (Federally recognized) Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Private institutions of higher education County governments Small businesses For profit organizations other than small businesses Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to invite cooperative agreement applications for the Tissue Chip Testing Center (TCTC) Microphysiological Systems (MPS) Data Center (MPS DC), which supports the NIH Tissue Chip Consortium. The Consortium facilitates the development, validation and dissemination of tissue chip (TC) technology through support for collaborative research in 1) development of tissue chips for toxicity and safety testing of promising therapeutics (RFA-RM-11-022); 2) development of tissue chips for disease modeling and efficacy testing (RFA-TR-16-017 and RFA-TR-16-019); and 3) independent validation of tissue chip platforms through the TCTCs (RFA-TR-16-006). The MPS DC is expected to be the central clearinghouse for TC data management, and will incorporate novel approaches and technologies for data management, data mining and meta-analyses, and data sharing across many organs and tissues, diseases, data types, and TC platforms. The MPS Data center is expected to provide different levels of public and tiered access to TC information for basic and clinical researchers, academic and practicing physicians, the pharmaceutical industry, NIH, FDA and other government agencies, patients, and the lay public. The MPS Data Center will work with IQ Consortium members to develop and make available a secure, customizable coordinated data management system for collection, storage, and analyses of diverse data types from multiple TC platforms being developed and used for drug screening, safety and efficacy testing. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-18-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00237182 | Feb 21, 2018 | Mar 21, 2018 | View |
Package 1
Mandatory forms
299571 RR_SF424_2_0-2.0.pdf
299571 PHS398_CoverPageSupplement_4_0-4.0.pdf
299571 RR_OtherProjectInfo_1_4-1.4.pdf
299571 PerformanceSite_2_0-2.0.pdf
299571 RR_KeyPersonExpanded_2_0-2.0.pdf
299571 RR_Budget_1_4-1.4.pdf
299571 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
299571 RR_SubawardBudget30_1_4-1.4.pdf
299571 PHS_AssignmentRequestForm_2_0-2.0.pdf
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