The National Institutes of Health (NIH) is offering a grant to establish a Model Organisms Screening Center for Phase II of the Undiagnosed Diseases Network (UDN). This grant aims to evaluate and analyze approximately 200 gene variants per year identified through the UDN using Drosophila and zebrafish models. The chosen center will develop a screening strategy to select informative variants and utilize additional small animal models or cell-based assays when necessary. This opportunity, funded by the NIH Common Fund, seeks to enhance understanding of pathogenicity and function of UDN gene variants and their correlation to disease phenotypes in participants.
Opportunity ID: 296516
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-17-017 |
| Funding Opportunity Title: | Model Organisms Screening Center for the Undiagnosed Diseases Network (UDN) Phase II (U54) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 15, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 02, 2017 |
| Current Closing Date for Applications: | Nov 02, 2017 |
| Archive Date: | Dec 08, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities State governments Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Independent school districts City or township governments Special district governments Native American tribal governments (Federally recognized) Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to provide a Model Organisms Screening Center for Phase II of the Undiagnosed Diseases Network (UDN). The Center will evaluate the pathogenicity and function of approximately 200 gene variants per year identified through the UDN. Responsive applications will propose to establish a screening strategy for selecting the most informative variants for analysis, and a research platform involving at a minimum Drosophila and zebrafish models. The screening pipeline may include additional small animal models or cell-based assays, as appropriate, to analyze the function of UDN gene variants in the context of the respective UDN participants disease phenotype. This initiative is funded through the NIH Common Fund which supports cross-cutting programs that are expected to have exceptionally high impact. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | FORMS-D | PKG00234320 | Oct 02, 2017 | Nov 02, 2017 | View |
Package 1
Mandatory forms
296516 RR_SF424_2_0-2.0.pdf
296516 PHS398_CoverPageSupplement_3_0-3.0.pdf
296516 RR_OtherProjectInfo_1_3-1.3.pdf
296516 PerformanceSite_2_0-2.0.pdf
296516 RR_KeyPersonExpanded_2_0-2.0.pdf
296516 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
296516 PHS_Additional_IndirectCosts-1.0.pdf
296516 PHS_AssignmentRequestForm-1.0.pdf
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