The National Institutes of Health’s National Institute on Drug Abuse (NIDA) is offering this grant to foster the development of essential tools for decentralized clinical trials (DCTs) in substance use disorder (SUD) research. This grant is for the purpose of bridging critical gaps hindering DCT adoption. A primary need is for validated, wearable, and home-use devices capable of accurately detecting substances like methadone, buprenorphine, and illicit drugs for diagnostic or treatment applications, as current options are largely absent or laboratory-focused. Furthermore, existing physiological sensors require further validation, and many developing devices lack standard software interfaces for seamless data transmission. This initiative seeks to drive the creation of robust, integrated technologies, enhancing the efficacy and reach of DCTs in SUD studies.
Opportunity ID: 350721
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-25-052 |
| Funding Opportunity Title: | Tools for decentralized clinical trials for substance use disorder (R43/R44 Clinical Trials Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 25, 2023 |
| Last Updated Date: | Oct 25, 2023 |
| Original Closing Date for Applications: | Mar 14, 2024 |
| Current Closing Date for Applications: | Mar 14, 2024 |
| Archive Date: | Apr 19, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $295,924 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | There are gaps that prevent the utilization of decentralized clinical trials (DCT) in substance use area. The existing sensors for physiological measurement are rarely used and may need further validation. There are no wearable or home-use detection devices on the market capable to measure substances of interest (e.g., methadone, buprenorphine, their metabolites, as well as the spectrum of illicit drugs). The devices in development are not intended for diagnostics or treatment. Most of the devices are intended for laboratory use. Most of the devices do not have standard software interface through which the devices can transmit the data to the study center. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-052.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350721 Full Announcement-RFA-DA-25-052 -> RFA-DA-25-052-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283604 | Feb 14, 2024 | Mar 14, 2024 | View |
Package 1
Mandatory forms
350721 RR_SF424_5_0-5.0.pdf
350721 PHS398_CoverPageSupplement_5_0-5.0.pdf
350721 RR_OtherProjectInfo_1_4-1.4.pdf
350721 PerformanceSite_4_0-4.0.pdf
350721 RR_KeyPersonExpanded_4_0-4.0.pdf
350721 RR_Budget_3_0-3.0.pdf
350721 PHS398_ResearchPlan_5_0-5.0.pdf
350721 SBIR_STTR_Information_3_0-3.0.pdf
350721 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350721 RR_SubawardBudget30_3_0-3.0.pdf
350721 PHS_AssignmentRequestForm_3_0-3.0.pdf
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