This grant, offered through the NIH R01 mechanism, invites highly innovative research proposals focusing on the epigenetic basis of human diseases. The purpose is to investigate and define epigenetic marks or features and their interactions within cells and tissues representing various human disease states or conditions. Studies should also explore the mechanisms by which these epigenetic changes occur in compromised states and how they lead to observable phenotypic differences. This funding opportunity aims to advance our understanding of epigenomics in the context of human health and disease. Approximately $6.7 million is available to support 10-15 awards.
Opportunity ID: 55652
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-10-002 |
| Funding Opportunity Title: | Epigenomics of Human Health and Disease (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 07, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 29, 2010 |
| Current Closing Date for Applications: | Sep 29, 2010 |
| Archive Date: | Oct 30, 2010 |
| Estimated Total Program Funding: | $5,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) County governments City or township governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This funding opportunity announcement (FOA) invites applications proposing highly innovative research that will investigate the epigenetic basis of human diseases. These studies will discover and define epigenetic marks or features and their possible interactions in cells and tissues that are representative of various human disease states, conditions or processes. Studies may also investigate the mechanism by which epigenetic changes occur in diseased or otherwise compromised states, and how these changes result in phenotypic differences. Mechanism of Support. This FOA will utilize the R01 award mechanism. Funds Available and Anticipated Number of Awards. The participating agencies intend to commit a total of $6.7 million. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. The anticipated number of awards is 10-15. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-10-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00019576 | Aug 29, 2010 | Sep 29, 2010 | View |
Package 1
Mandatory forms
55652 RR_SF424_1_2-1.2.pdf
55652 PerformanceSite_1_3-1.3.pdf
55652 RR_OtherProjectInfo_1_2-1.2.pdf
55652 RR_KeyPersonExpanded_1_2-1.2.pdf
55652 PHS398_CoverPageSupplement_1_4-1.4.pdf
55652 PHS398_ResearchPlan_1_3-1.3.pdf
55652 PHS398_Checklist_1_3-1.3.pdf
Optional forms
55652 PHS_CoverLetter_1_2-1.2.pdf
55652 PHS398_ModularBudget-1.1.pdf
55652 RR_Budget-1.1.pdf
55652 RR_SubawardBudget-1.2.pdf
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