The National Institutes of Health (NIH) is offering this R21 grant to advance fundamental functional genetic and genomic research in the field of substance abuse. This grant is for the purpose of moving beyond gene discovery to understand the molecular mechanisms underpinning addictive processes. Specifically, it encourages studies in two key areas: validating the authentic role of candidate genes, gene variants, epigenetic features, and non-coding RNAs in addiction, and deeply elucidating the molecular pathways and processes modulated by these candidates, particularly those with previously unanticipated roles in addiction. The aim is to bridge the gap between genetic identification and mechanistic understanding of addiction.
Opportunity ID: 248926
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-14-013 |
| Funding Opportunity Title: | Functional Genetics, Epigenetics, and Non-coding RNAs in Substance Abuse (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2017 |
| Current Closing Date for Applications: | Jan 07, 2017 |
| Archive Date: | Feb 07, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts County governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Genetic and genomic studies have identified genes and gene variants that potentially modulate the fundamental biological mechanisms underpinning addictive processes. Discovery of these genes/variants, while extremely valuable, is only a first step in understanding molecular mechanisms of addiction. This Funding Opportunity Announcement encourages basic functional genetic and genomic research in two areas: 1. functional validation to determine which candidate genes/variants/epigenetic/non-coding RNA features have an authentic role in addictive processes, and 2. detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in addiction. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-14-013.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.279 | FORMS-C | Forms-C | PKG00190739 | Jan 16, 2014 | May 07, 2016 | View |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222397 | Apr 17, 2016 | Jan 07, 2017 | View |
Package 1
Mandatory forms
248926 RR_SF424_2_0-2.0.pdf
248926 PHS398_ResearchPlan_2_0-2.0.pdf
248926 PHS398_CoverPageSupplement_2_0-2.0.pdf
248926 RR_KeyPersonExpanded_2_0-2.0.pdf
248926 RR_OtherProjectInfo_1_3-1.3.pdf
248926 PerformanceSite_2_0-2.0.pdf
Optional forms
248926 RR_SubawardBudget30_1_3-1.3.pdf
248926 PlannedReport-1.0.pdf
248926 PHS398_CumulativeInclusionReport-1.0.pdf
248926 PHS398_ModularBudget_1_2-1.2.pdf
248926 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
248926 RR_SF424_2_0-2.0.pdf
248926 PHS398_CoverPageSupplement_3_0-3.0.pdf
248926 RR_OtherProjectInfo_1_3-1.3.pdf
248926 PerformanceSite_2_0-2.0.pdf
248926 RR_KeyPersonExpanded_2_0-2.0.pdf
248926 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
248926 RR_Budget_1_3-1.3.pdf
248926 RR_SubawardBudget30_1_3-1.3.pdf
248926 PHS398_ModularBudget_1_2-1.2.pdf
248926 PHS_Inclusion_Enrollment_Report-1.0.pdf
248926 PHS_AssignmentRequestForm-1.0.pdf
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