This NIH R21 grant is designed to support innovative research investigating the complex relationship between autophagy-regulated cell death and HIV pathogenesis. The primary purpose is to explore how these biological processes interact, specifically focusing on their impact within the central nervous system (CNS) cellular immune responses. A crucial aspect of this research is understanding how acute and chronic drug use influences these intricate pathways. This funding opportunity seeks projects that will deepen our understanding of HIV’s progression and its cellular mechanisms in the context of substance use disorders, potentially leading to new insights into prevention and treatment strategies.
Opportunity ID: 351345
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-25-010 |
| Funding Opportunity Title: | Interplay of Autophagy Regulated Cell Death and HIV Pathogenesis in Substance Use Disorders (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 06, 2023 |
| Last Updated Date: | Dec 06, 2023 |
| Original Closing Date for Applications: | Nov 14, 2024 |
| Current Closing Date for Applications: | Nov 14, 2024 |
| Archive Date: | Dec 20, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) County governments Special district governments Public and State controlled institutions of higher education City or township governments Small businesses Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The Notice of Funding Opportunity (NOFO) aims to support research addressing the interplay of autophagy orchestrated cell death and HIV pathogenesis with a focus on the CNS cellular immune responses influenced by acute and chronic drug use. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 351345 Full Announcement-RFA-DA-25-010 -> RFA-DA-25-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00284054 | Oct 14, 2024 | Nov 14, 2024 | View |
Package 1
Mandatory forms
351345 RR_SF424_5_0-5.0.pdf
351345 PHS398_CoverPageSupplement_5_0-5.0.pdf
351345 RR_OtherProjectInfo_1_4-1.4.pdf
351345 PerformanceSite_4_0-4.0.pdf
351345 RR_KeyPersonExpanded_4_0-4.0.pdf
351345 PHS398_ResearchPlan_5_0-5.0.pdf
351345 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
351345 RR_Budget_3_0-3.0.pdf
351345 RR_SubawardBudget30_3_0-3.0.pdf
351345 PHS398_ModularBudget_1_2-1.2.pdf
351345 PHS_AssignmentRequestForm_3_0-3.0.pdf
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