This NIH Small Business Innovative Research (SBIR) grant is offering funding to small business concerns (SBCs) to develop novel medium- to high-throughput assays. This grant is for the purpose of evaluating the effects of chemical toxicants on pluripotent or induced pluripotent cells, specifically focusing on their differentiation into specialized cell populations. A crucial aspect is the ability to incorporate genetic diversity into these assays. The outputs of this research will provide vital information on the mechanisms of chemically-induced biological activity, help prioritize chemicals for more extensive toxicological evaluation, support enhanced predictive models of in vivo biological responses, and inform on the role of genetic diversity in toxicological effects.
Opportunity ID: 294941
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-17-007 |
| Funding Opportunity Title: | Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR R44) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 23, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 04, 2017 |
| Current Closing Date for Applications: | Oct 04, 2017 |
| Archive Date: | Nov 09, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. See Funding Opportunity Announcements for Eligibility Details |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful. These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-17-007.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00233379 | Sep 04, 2017 | Oct 04, 2017 | View |
Package 1
Mandatory forms
294941 RR_SF424_2_0-2.0.pdf
294941 PHS398_CoverPageSupplement_3_0-3.0.pdf
294941 RR_OtherProjectInfo_1_3-1.3.pdf
294941 PerformanceSite_2_0-2.0.pdf
294941 RR_KeyPersonExpanded_2_0-2.0.pdf
294941 RR_Budget_1_3-1.3.pdf
294941 PHS398_ResearchPlan_3_0-3.0.pdf
294941 SBIR_STTR_Information_1_1-1.1.pdf
Optional forms
294941 RR_SubawardBudget30_1_3-1.3.pdf
294941 PHS_Inclusion_Enrollment_Report-1.0.pdf
294941 PHS_AssignmentRequestForm-1.0.pdf
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