The National Institutes of Health is offering a grant for small businesses to develop innovative in vitro screening systems using animal-derived cells for toxicity testing. The goal is to create physiologically-relevant models that replicate animal tissue interactions and toxicological responses, producing data comparable to in vivo studies. This grant aims to provide alternative methods to reduce animal use in toxicity testing. Closing date for proposals is Jan 3, 2020.
Opportunity ID: 321480
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-20-005 |
| Funding Opportunity Title: | Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43/R44 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 10, 2019 |
| Last Updated Date: | Oct 10, 2019 |
| Original Closing Date for Applications: | Jan 03, 2020 |
| Current Closing Date for Applications: | Jan 03, 2020 |
| Archive Date: | Feb 08, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) supports Phase I (R43), Phase II (R44), Direct Phase II (R44) and Fast Track (R44) Small Business Innovative Research (SBIR) grant proposals from small businesses concerns (SBCs) to develop novel, physiologically-relevant in vitro screening systems (e.g., engineered 3-dimensional or organotypic models) using cells derived from animal species typically utilized for toxicological testing, which will replicate biological interactions and toxicological responses observed in animal tissues or organs, will produce assay data suitable for comparisons between in vitro and in vivo animal toxicology studies, and may ultimately provide alternative methods to reduce the use of animals in toxicity testing. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-20-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00255765 | Dec 03, 2019 | Jan 03, 2020 | View |
Package 1
Mandatory forms
321480 RR_SF424_2_0-2.0.pdf
321480 PHS398_CoverPageSupplement_4_0-4.0.pdf
321480 RR_OtherProjectInfo_1_4-1.4.pdf
321480 PerformanceSite_2_0-2.0.pdf
321480 RR_KeyPersonExpanded_2_0-2.0.pdf
321480 RR_Budget_1_4-1.4.pdf
321480 PHS398_ResearchPlan_4_0-4.0.pdf
321480 SBIR_STTR_Information_1_2-1.2.pdf
Optional forms
321480 RR_SubawardBudget30_1_4-1.4.pdf
321480 PHS_AssignmentRequestForm_2_0-2.0.pdf
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