The National Institutes of Health is offering a grant to support research in spermatogenic stem cell biology, aiming to preserve and restore male reproductive capacity. The grant focuses on developing culture systems to expand SSCs, removing malignant cells post-treatment, and potential applications in drug development and toxicity testing. The goal is to improve the chances of natural conception without assisted reproductive technologies. Closing date: Jun 05, 2018.
Opportunity ID: 281776
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-16-114 |
| Funding Opportunity Title: | Spermatogenic Stem Cell Culture Systems to Preserve and Restore Reproductive Capacity in Males (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.865 — Child Health and Human Development Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 25, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 05, 2018 |
| Current Closing Date for Applications: | Jun 05, 2018 |
| Archive Date: | Jul 06, 2018 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Small businesses Independent school districts County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities City or township governments State governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of spermatogenic stem cell (SSC) biology.The overarching goal is to increase the chances that couples may have biological offspring without using conventional assisted reproductive modalities (i.e., IVF, ICSI).A focal point of the initiative is on the development of new techniques to culture and expand these cells over an extended period of time.Another area of study includes methods to eliminate malignant cells from SSC cultures following chemotherapy/radiation treatment. Also, spermatogenic stem cells from human adults could have a major impact on drug development and toxicity testing as animal-based systems do not sufficiently mirror the situation in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-16-114.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or before January 24, 2018 | PKG00221576 | May 05, 2016 | Jan 24, 2018 | View | |
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00235787 | Nov 06, 2017 | Jun 05, 2018 | View |
Package 1
Mandatory forms
281776 RR_SF424_2_0-2.0.pdf
281776 PHS398_CoverPageSupplement_3_0-3.0.pdf
281776 RR_OtherProjectInfo_1_3-1.3.pdf
281776 PerformanceSite_2_0-2.0.pdf
281776 RR_KeyPersonExpanded_2_0-2.0.pdf
281776 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
281776 RR_Budget_1_3-1.3.pdf
281776 RR_SubawardBudget30_1_3-1.3.pdf
281776 PHS398_ModularBudget_1_2-1.2.pdf
281776 PHS_Inclusion_Enrollment_Report-1.0.pdf
281776 PHS_AssignmentRequestForm-1.0.pdf
Package 2
Mandatory forms
281776 RR_SF424_2_0-2.0.pdf
281776 PHS398_CoverPageSupplement_4_0-4.0.pdf
281776 RR_OtherProjectInfo_1_4-1.4.pdf
281776 PerformanceSite_2_0-2.0.pdf
281776 RR_KeyPersonExpanded_2_0-2.0.pdf
281776 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
281776 RR_Budget_1_4-1.4.pdf
281776 RR_SubawardBudget30_1_4-1.4.pdf
281776 PHS398_ModularBudget_1_2-1.2.pdf
281776 PHS_AssignmentRequestForm_2_0-2.0.pdf
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