The National Institutes of Health (NIH) is offering this grant to advance our understanding of how Epstein Barr virus (EBV) infection contributes to the development of Non-Hodgkin Lymphoma (NHL) and Hodgkin disease (HD). This grant is for supporting comprehensive research, including mechanistic, epidemiological, and translational studies, that thoroughly investigate EBV’s role in the initiation, progression, and resulting sequelae of these lymphomas. A primary purpose is to gain critical insights into the differing mechanisms of EBV infection and lymphomagenesis observed in individuals both with and without underlying HIV infection. This research aims to illuminate the complex interplay between EBV, HIV, and lymphoma development, ultimately informing improved prevention and treatment strategies.
Opportunity ID: 335952
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-21-348 |
| Funding Opportunity Title: | The role of Epstein Barr virus (EBV) infection in Non-Hodgkin Lymphoma (NHL) and Hodgkin disease (HD) development with or without an underlying HIV infection (U01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 28, 2021 |
| Last Updated Date: | Sep 28, 2021 |
| Original Closing Date for Applications: | Dec 15, 2023 |
| Current Closing Date for Applications: | Dec 15, 2023 |
| Archive Date: | Jan 20, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Native American tribal governments (Federally recognized) Special district governments Private institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The role of EBV infection on Non-Hodgkin Lymphoma (NHL) and Hodgkin disease (HD) development with or without an underlying HIV infection and AIDS will increase our understanding through mechanistic, epidemiological, or translational studies that examine how EBV promotes NHL or HD initiation, progression and the resulting disease sequelae. In addition, insights into mechanistic differences of EBV infection and lymphomagenesis between HIV positive and HIV negative persons will be gained. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-21-348.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 335952 Full Announcement-PAR-21-348 -> PAR-21-348-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00269120 | Nov 15, 2021 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00270429 | Nov 18, 2021 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277953 | Nov 04, 2022 | Dec 15, 2023 | View |
Package 1
Mandatory forms
335952 RR_SF424_2_0-2.0.pdf
335952 PHS398_CoverPageSupplement_5_0-5.0.pdf
335952 RR_OtherProjectInfo_1_4-1.4.pdf
335952 PerformanceSite_2_0-2.0.pdf
335952 RR_KeyPersonExpanded_2_0-2.0.pdf
335952 PHS398_ResearchPlan_4_0-4.0.pdf
335952 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335952 RR_Budget_1_4-1.4.pdf
335952 RR_SubawardBudget30_1_4-1.4.pdf
335952 PHS398_ModularBudget_1_2-1.2.pdf
335952 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335952 RR_SF424_5_0-5.0.pdf
335952 PHS398_CoverPageSupplement_5_0-5.0.pdf
335952 RR_OtherProjectInfo_1_4-1.4.pdf
335952 PerformanceSite_4_0-4.0.pdf
335952 RR_KeyPersonExpanded_4_0-4.0.pdf
335952 PHS398_ResearchPlan_4_0-4.0.pdf
335952 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335952 RR_Budget_3_0-3.0.pdf
335952 RR_SubawardBudget30_3_0-3.0.pdf
335952 PHS398_ModularBudget_1_2-1.2.pdf
335952 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
335952 RR_SF424_5_0-5.0.pdf
335952 PHS398_CoverPageSupplement_5_0-5.0.pdf
335952 RR_OtherProjectInfo_1_4-1.4.pdf
335952 PerformanceSite_4_0-4.0.pdf
335952 RR_KeyPersonExpanded_4_0-4.0.pdf
335952 PHS398_ResearchPlan_5_0-5.0.pdf
335952 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335952 RR_Budget_3_0-3.0.pdf
335952 RR_SubawardBudget30_3_0-3.0.pdf
335952 PHS398_ModularBudget_1_2-1.2.pdf
335952 PHS_AssignmentRequestForm_3_0-3.0.pdf
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