The NIH’s Gabriella Miller Kids First Pediatric Research Program is offering this grant to advance the genetic understanding of childhood cancers and structural birth defects. This program invites applications for researchers to submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported center. This grant is for the purpose of elucidating the genetic contribution (somatic and/or germline) to childhood cancers or expanding the Kids First Data Resource to investigate the genetic etiology of structural birth defects. Proposals for whole genome, exome, transcriptome sequencing, and justified epigenomic assays are accepted. All generated data will contribute to the Gabriella Miller Kids First Pediatric Data Resource for the wider pediatric research community.
Opportunity ID: 336388
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-054 |
| Funding Opportunity Title: | Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 02, 2021 |
| Last Updated Date: | Nov 02, 2021 |
| Original Closing Date for Applications: | Feb 23, 2022 |
| Current Closing Date for Applications: | Feb 23, 2022 |
| Archive Date: | Mar 31, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments For profit organizations other than small businesses State governments Small businesses Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Private institutions of higher education County governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, or to expand the range of disorders included within the Kids First Data Resource to investigate the genetic etiology of structural birth defects. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as epigenomic assays of tumor or affected tissue, when justified. These data, and associated clinical and phenotypic data, will become part of the Gabriella Miller Kids First Pediatric Data Resource (Kids First Data Resource) for the pediatric research community. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-054.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 336388 Full Announcement-PAR-22-054 -> PAR-22-054-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00269993 | Jan 24, 2022 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270577 | Jan 24, 2022 | Feb 23, 2022 | View |
Package 1
Mandatory forms
336388 RR_SF424_2_0-2.0.pdf
336388 PHS398_CoverPageSupplement_5_0-5.0.pdf
336388 RR_OtherProjectInfo_1_4-1.4.pdf
336388 RR_KeyPersonExpanded_2_0-2.0.pdf
336388 PHS398_ResearchPlan_4_0-4.0.pdf
336388 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
336388 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
336388 RR_SF424_5_0-5.0.pdf
336388 PHS398_CoverPageSupplement_5_0-5.0.pdf
336388 RR_OtherProjectInfo_1_4-1.4.pdf
336388 RR_KeyPersonExpanded_4_0-4.0.pdf
336388 PHS398_ResearchPlan_4_0-4.0.pdf
336388 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
336388 PHS_AssignmentRequestForm_3_0-3.0.pdf
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