This grant, a joint initiative from the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Mental Health (NIMH), supports exploratory and innovative neuroscience research. It funds the early, conceptual stages of projects that, despite considerable risk, have the potential for breakthroughs in understanding neuroscience or developing novel techniques, agents, methodologies, or models. These studies assess the feasibility of new avenues of investigation, aiming for high value to the neuroscience community. While general clinical trials are not allowed, the grant specifically welcomes applications proposing mechanistic clinical trials or basic experimental studies with humans (BESH).
Opportunity ID: 358075
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-25-150 |
| Funding Opportunity Title: | Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 08, 2025 |
| Last Updated Date: | Jan 08, 2025 |
| Original Closing Date for Applications: | Jan 07, 2028 |
| Current Closing Date for Applications: | Jan 07, 2028 |
| Archive Date: | Feb 12, 2028 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Independent school districts For profit organizations other than small businesses County governments Special district governments Private institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The Joint NINDS/NIMH Exploratory Neuroscience Research Grant program supports exploratory and innovative research projects, which fall within the missions of the NINDS and NIMH. Awards will provide support for the early and conceptual stages of projects. These studies often assess the feasibility of a novel avenue of investigation and involve considerable risk, but have the potential to bring about breakthroughs in the understanding of important areas of neuroscience, or to the development of novel techniques, agents, methodologies, or models, of high value to the neuroscience community. While this funding opportunity also accepts clinical trials, only applications proposing mechanistic clinical trials or studies or basic experimental studies with humans (BESH) will be considered for funding. For information on the types of clinical trial that are within scope of this funding opportunity announcement, refer to Funding Opportunity Description, below. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PA-25-150.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358075 Full Announcement-PA-25-150 -> PA-25-150-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289944 | Jan 16, 2025 | Jan 07, 2028 | View |
Package 1
Mandatory forms
358075 RR_SF424_5_0-5.0.pdf
358075 PHS398_CoverPageSupplement_5_0-5.0.pdf
358075 RR_OtherProjectInfo_1_4-1.4.pdf
358075 PerformanceSite_4_0-4.0.pdf
358075 RR_KeyPersonExpanded_4_0-4.0.pdf
358075 PHS398_ResearchPlan_5_0-5.0.pdf
358075 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358075 RR_Budget_3_0-3.0.pdf
358075 RR_SubawardBudget30_3_0-3.0.pdf
358075 PHS398_ModularBudget_1_2-1.2.pdf
358075 PHS_AssignmentRequestForm_4_0-4.0.pdf
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