The National Institute of Neurological Disorders and Stroke (NINDS) is offering this grant to establish a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC) for the Parkinson’s Disease Biomarker Identification Network (PD-BIN). This initiative aims to identify biological markers for PD risk, onset, and progression, thereby facilitating disease-modifying treatments. The CCC will manage subject recruitment, specimen acquisition, and clinical site oversight, ensuring accurate data collection. Concurrently, the DCC will provide comprehensive data management, including standardization, quality control, and public dissemination. The acquired data and biospecimens from this multi-site network will form a publicly available resource for biomarker validation and discovery. Both centers are expected to advance the scientific goal of identifying and validating useful PD biomarkers.
Opportunity ID: 58168
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-11-005 |
| Funding Opportunity Title: | Clinical and Data Coordinating Center(s) for Parkinsons Disease Biomarkers Identification Network (PD-BIN) (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 24, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 18, 2011 |
| Current Closing Date for Applications: | Jan 18, 2011 |
| Archive Date: | Feb 18, 2011 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Independent school districts State governments Small businesses Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NINDS intends to fund a multi-site, multi-project network (Parkinsons Disease Biomarker Identification Network, or PD-BIN) devoted to identifying biological markers for PD risk, onset, and/or progression, in order to facilitate development of disease-modifying treatments. The purpose of this FOA is to solicit linked cooperative agreement (U01) applications for the establishment of a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC). The PIs for the DCC and CCC must coordinate their submissions. The CCC will be responsible for the oversight of all aspects of subject recruitment and specimen acquisition, including the management of multiple clinical sites (to be identified by the CCC applicant), enrollment of a core cohort of newly diagnosed patients with PD and matched controls, and accurate collection of all clinical and biological data. The DCC will provide all data management aspects for standardized acquisition, quality control, dissemination and public accessibility. The CCC and DCC must be flexible enough to accommodate and support a wide range of future add-on research projects seeking to utilize and augment the core PD-BIN data. Individual hypothesis-driven studies are not a component of this FOA. It is anticipated that all data and biospecimens acquired will be used to create a publicly available resource for biomarker validation and discovery. The CCC and the DCC will be expected to advance the general scientific goal of identifying and validating useful PD biomarkers. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-11-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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